Results 21 to 30 of about 29,796 (189)

Metformin Induces PRODH/POX-Dependent Apoptosis in Breast Cancer Cells

open access: yesFrontiers in Molecular Biosciences, 2022
Although the antineoplastic activity of metformin (MET) is well established, the underlying mechanism of the activity is not understood. Since MET activates AMP kinase (AMPK) and proline dehydrogenase/proline oxidase (PRODH/POX) is stimulated by AMPK ...
Thi Yen Ly Huynh   +8 more
doaj   +1 more source

Exogenous Proline Alleviated Low Temperature Stress in Maize Embryos by Optimizing Seed Germination, Inner Proline Metabolism, Respiratory Metabolism and a Hormone Regulation Mechanism

open access: yesAgriculture, 2022
Proline (Pro) is not only an important osmotic adjustment substance, but it also plays an important role in regulating plant abiotic stress resistance. The maize varieties, Xinxin 2 (low temperature insensitive) and Damin 3307 (low temperature sensitive),
Shiyu Zuo, Jing Li, Wanrong Gu, Shi Wei
doaj   +1 more source

Exogenous Proline Enhances Systemic Defense against Salt Stress in Celery by Regulating Photosystem, Phenolic Compounds, and Antioxidant System

open access: yesPlants, 2023
This study aimed to explore how exogenous proline induces salinity tolerance in celery. We analyzed the effects of foliar spraying with 0.3 mM proline on celery growth, photosystem, phenolic compounds, and antioxidant system under salt stress (100 mM ...
Yanqiang Gao   +8 more
doaj   +1 more source

Seed bio-priming with beneficial Trichoderma harzianum alleviates cold stress in maize [PDF]

open access: yesPeerJ, 2023
Maize is one of the major crops in the world and the most productive member of the Gramineae family. Since cold stress affects the germination, growth, and productivity of corn seeds, the present study aimed to investigate the effect of seed biopriming ...
Mehdi Afrouz   +5 more
doaj   +2 more sources

Studying the physiological and yield responses of sunflower inbred lines to full and limited irrigation

open access: yesJournal of Integrative Agriculture, 2018
In order to study the physiological and yield responses of sunflower inbred lines to full and limited irrigation, an experiment was conducted in the growing season of 2014–2015 in the research field of the Agricultural Research Station in Khoi, Iran ...
Nasserghadimi Farshad   +3 more
doaj   +1 more source

Exogenous Proline, Methionine, and Melatonin Stimulate Growth, Quality, and Drought Tolerance in Cauliflower Plants

open access: yesAgriculture, 2022
The impact of proline, methionine, and melatonin on cauliflower plants under drought stress is still unclear in the available publications. So, this research aims to study these biochemical compounds’ effects on cauliflower plants grown under well ...
Hemat A. EL-Bauome   +13 more
doaj   +1 more source

Regulation of proline oxidase activity by lactate. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1977
We found that proline oxidase, the first enzyme of the proline degradative pathway, is inhibited by lactate. The Km of the enzyme for proline increases with increasing concentrations of lactate. Since proline can be a source for gluconeogenesis, regulation of proline degradation by lactate may serve as a mechanism for allocation of metabolic fuel ...
E M, Kowaloff   +3 more
openaire   +2 more sources

Constituents of Propolis: Chrysin, Caffeic Acid, p-Coumaric Acid, and Ferulic Acid Induce PRODH/POX-Dependent Apoptosis in Human Tongue Squamous Cell Carcinoma Cell (CAL-27)

open access: yesFrontiers in Pharmacology, 2018
Propolis evokes several therapeutic properties, including anticancer activity. These activities are attributed to the action of polyphenols. Previously it has been demonstrated, that one of the most abundant polyphenolic compounds in ethanolic extracts ...
Katarzyna Celińska-Janowicz   +6 more
doaj   +1 more source

Proline dehydrogenase regulates redox state and respiratory metabolism in Trypanosoma cruzi. [PDF]

open access: yesPLoS ONE, 2013
Over the past three decades, L-proline has become recognized as an important metabolite for trypanosomatids. It is involved in a number of key processes, including energy metabolism, resistance to oxidative and nutritional stress and osmoregulation.
Lisvane Silva Paes   +8 more
doaj   +1 more source

Understanding the Role of Estrogen Receptor Status in PRODH/POX-Dependent Apoptosis/Survival in Breast Cancer Cells

open access: yesBiology, 2021
It has been suggested that activation of estrogen receptor α (ER α) stimulates cell proliferation. In contrast, estrogen receptor β (ER β) has anti-proliferative and pro-apoptotic activity.
Sylwia Lewoniewska   +3 more
doaj   +1 more source

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