Regulation and function of proline oxidase under nutrient stress [PDF]
AbstractUnder conditions of nutrient stress, cells switch to a survival mode catabolizing cellular and tissue constituents for energy. Proline metabolism is especially important in nutrient stress because proline is readily available from the breakdown of extracellular matrix (ECM), and the degradation of proline through the proline cycle initiated by ...
Jui, Pandhare +3 more
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MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells [PDF]
Proline oxidase (POX), localized on inner mitochondrial membranes, is encoded by a p53-induced gene and metabolically participates in p53-induced apoptosis. Previously, we showed that POX catalyzed the generation of reactive oxygen species (ROS). We and others have demonstrated that overexpression of POX, independent of p53, causes apoptotic cell death
Yongmin, Liu +7 more
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Proline metabolism regulates replicative lifespan in the yeast Saccharomyces cerevisiae
In many plants and microorganisms, intracellular proline has a protective role against various stresses, including heat-shock, oxidation and osmolarity. Environmental stresses induce cellular senescence in a variety of eukaryotes.
Yukio Mukai +7 more
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Evaluation of Application of the Asparagine and Glutamine Amino Acids on Improving the Biochemical Properties and Yield under Drought Sterss Conditions on Pistachio cv. Shahpsand [PDF]
This experiment was performed to investigate the effect of foliar application of amino acids on improving biochemical properties and yield evaluation of the effect of drought stress on pistachio, cv.
Mohammad ali Khajezade +3 more
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The proline regulatory axis and cancer
Studies in metabolism and cancer have characterized changes in core pathways involving glucose and glutamine, emphasizing the provision of substrates for building cell mass.
James Ming Phang
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The postharvest life of flat peach fruit is limited by the appearance of chilling injury symptoms, especially internal browning. In this study, impacts of the exogenous application of proline (0, 5, 10, and 15 mM) and L-cysteine (0, 0.2, 0.4 and 0.6%) on
Gholamreza Gohari +6 more
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The Effects of Endophytic Fungus Piriformospora indica on Morphophysiological Traits of Pyrus Rootstock cv. Pyrodvarf under Salinity Stress Conditions [PDF]
Background & Objective: The pear is one of the most important fruit trees in temperate regions and is salt-sensitive trees. Studies have shown that the use of Piriformospora indica as an endophytic fungus reduces the adverse effects of salinity stress on
Mohammad Adlipour +4 more
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The effects of exogenously-sourced NO (nitric oxide, as 100 µM SNP) and proline (50 mM) in the protection of the photosynthetic performance of wheat (Triticum aestivum L.) plants against heat stress were investigated.
Zebus Sehar +4 more
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Proline Oxidase Promotes Tumor Cell Survival in Hypoxic Tumor Microenvironments [PDF]
Abstract Proline is a readily released stress substrate that can be metabolized by proline oxidase (POX) to generate either reactive oxygen species (ROS) to induce apoptosis or autophagy or ATP during times of nutrient stress. However, the contribution of proline metabolism to tumorigenesis in hypoxic microenvironments has not been ...
Wei, Liu +5 more
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The effects of night temperature and nitric oxide on some physio-biochemical characters of Pea plants [PDF]
Introduction Plant responses to environmental stress have a central role in agricultural production. Responses results from events occurring at all levels of the organization, from biochemical reactions in cells to whole plant physiology. Many plants are
Nader Chaparzadeh, Masumeh Faraji
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