Results 81 to 90 of about 63,793 (252)

Hyperprolinemia Type IA

Journal of Inborn Errors of Metabolism and Screening, 2017
Objective: Hyperprolinemia type I (HPI) is a rare and inherited autosomal recessive disorder caused by proline oxidase deficiency. Hyperprolinemia type 1 is biochemically defined as high plasma proline levels without urinary Δ-1-pyrroline-5-carboxylate ...
Piero Pavone MD, Andrea D. Praticò MD, Giovanni Sorge MD, Concetta Meli MD, Martino Ruggieri MD, PhD, BA, Renata Rizzo MD, Agata Fiumara MD   +6 more
doaj   +1 more source

Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy [PDF]

Carcinogenesis, 2009
Epidemiological studies showed that high levels of oxidized low-density lipoproteins (oxLDLs) are associated with increased cancer risk. We examined the direct effect of physiologic concentrations oxLDL on cancer cells. OxLDLs were cytotoxic and activate both apoptosis and autophagy.
Zabirnyk, Olga, Liu, Wei, Khalil, Shadi, Sharma, Anit, Phang, James M.   +4 more
openaire   +2 more sources

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

Advanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang, Wenzhi Wang, Dongjiao Wang, Qibin Wu, Youxiong Que   +4 more
wiley   +1 more source

Evaluating Foliar Application of Calcium Nitrate, Calcium Chloride and Boric Acid on Physiological Disorders of ‘Kaleh - Ghoochi’ Pistachio [PDF]

Journal of Nuts, 2019
Pistachio suffers from some physiological disorders such as fruit abscission, endocarp lesion, blankness, non-split, early-split and deformed nuts. In this experiment, the effects of calcium nitrate (2 gr/lit), calcium chloride (2 gr/lit), boric acid ...
Ebrahim Pourahmadi, Abdorahman Mohamadkhani, Parto Roshandel, Somayeh Momenyan   +3 more
doaj   +1 more source

Hydrogen Sulfide Treatment Alleviates Chilling Injury in Cucumber Fruit by Regulating Antioxidant Capacity, Energy Metabolism and Proline Metabolism

Foods, 2022
Although low-temperature storage could maintain the quality of fruits and vegetables, it may also result in chilling injury (CI) in cold-sensitive produce, such as cucumbers.
Jingda Wang, Yaqin Zhao, Zhiqian Ma, Yonghua Zheng, Peng Jin   +4 more
doaj   +1 more source

Functional studies on oligotropha carboxidovorans molybdenum–copper CO dehydrogenase produced in escherichia coli [PDF]

, 2018
The Mo/Cu-dependent CO dehydrogenase (CODH) from Oligotropha carboxidovorans is an enzyme that is able to catalyze both the oxidation of CO to CO2 and the oxidation of H2 to protons and electrons. Despite the close to atomic resolution structure (1.1 Å),
Duffus, Benjamin R., Kaufmann, Paul, Leimkühler, Silke, Teutloff, Christian   +3 more
core   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Sustained AMPK Activation and Proline Metabolism Play Critical Roles in the Survival of Matrix-Deprived Transformed Cells

Frontiers in Cell and Developmental Biology, 2021
Attachment to the matrix is critical for the survival of adherent cells, whereas detachment triggers death by apoptosis. Therefore, solid tumors must acquire the ability to survive the stress of matrix-detachment to transit through circulation and seed ...
Manipa Saha, Neha Deshpande, Abhinav Dubey, Abhinav Dubey, Debnath Pal, Debnath Pal, Hanudatta S. Atreya, Hanudatta S. Atreya, Annapoorni Rangarajan   +8 more
doaj   +1 more source

Characterization of TrxC, an Atypical Thioredoxin Exclusively Present in Cyanobacteria [PDF]

, 2018
Cyanobacteria form a diverse group of oxygenic photosynthetic prokaryotes considered to be the antecessor of plant chloroplast. They contain four different thioredoxins isoforms, three of them corresponding to m, x and y type present in plant chloroplast,
Florencio Bellido, Francisco Javier, Heredia Martínez, Luis G., López Maury, Luis   +2 more
core   +1 more source

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

Food Biomacromolecules, EarlyView.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source