Results 1 to 10 of about 1,389,605 (343)
Nonlinear control of transcription through enhancer–promoter interactions
Nature, 2021 Chromosome structure in mammals is thought to regulate transcription by modulating three-dimensional interactions between enhancers and promoters, notably through CTCF-mediated loops and topologically associating domains (TADs)1–4.
J. Zuin +15 more
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Discrete Mathematics & Theoretical Computer Science, 2012 We present an equivariant bijection between two actions—promotion and rowmotion—on order ideals in certain posets. This bijection simultaneously generalizes a result of R. Stanley concerning promotion on the linear extensions of two disjoint chains and certain cases of recent work of D. Armstrong, C. Stump, and H.
Striker, Jessica, Williams, Nathan
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Promoting human promoters [PDF]
Molecular Systems Biology, 2006 Mol Syst Biol. 2: 2006.0030 The effect of transcription factors on human gene expression can now be quantified owing to a new computational approach. The method was successfully applied to the cases of the cell cycle program, and for liver‐specific gene expression. Transcriptional regulation of gene expression plays a major role in the acquisition of
Itay Furman, Yitzhak Pilpel
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Promoter-proximal CTCF-binding promotes long-range-enhancer dependent gene activation
Nature Structural & Molecular Biology, 2021 The CCCTC-binding factor (CTCF) works together with the cohesin complex to drive the formation of chromatin loops and topologically associating domains, but its role in gene regulation has not been fully defined.
Naoki Kubo +15 more
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Nucleic Acids Res., 2002 PlantCARE is a database of plant cis-acting regulatory elements, enhancers and repressors. Regulatory elements are represented by positional matrices, consensus sequences and individual sites on particular promoter sequences.
M. Lescot +7 more
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Nucleic Acids Research, 1984 A simple and efficient method for synthesizing pure single stranded RNAs of virtually any structure is described. This in vitro transcription system is based on the unusually specific RNA synthesis by bacteriophage SP6 RNA polymerase which initiates ...
D. Melton +5 more
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Isolating Price Promotions: The Influence of Promotional Timing on Promotion Redemption
Journal of the Association for Consumer Research, 2021 This research investigates how the timing of the promotional encounter, whether consumers encounter a promotion in isolation or at the moment of choice alongside other products, influences how consumers evaluate and redeem a promotional offer. Three studies demonstrate that isolated promotions for premium brands are more effective than traditional ...
Daniel Sheehan, Koert van Ittersum
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Proceedings of the National Academy of Sciences of the United States of America, 1985 The RNA polymerase gene of bacteriophage T7 has been cloned into the plasmid pBR322 under the inducible control of the lambda PL promoter. After induction, T7 RNA polymerase constitutes 20% of the soluble protein of Escherichia coli, a 200-fold increase ...
S. Tabor, C. Richardson
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Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors.
New England Journal of Medicine, 2015 BACKGROUND The prediction of clinical behavior, response to therapy, and outcome of infiltrative glioma is challenging. On the basis of previous studies of tumor biology, we defined five glioma molecular groups with the use of three alterations ...
J. Eckel-Passow +35 more
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Clinics in Colon and Rectal Surgery, 2013 This article gives an overview of the promotion process in an academic medical center. A description of different promotional tracks, tenure and endowed chairs, and the process of submitting an application is provided. Finally, some practical advice about developing skills and attributes that can help with academic growth and promotion is dispensed.
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