Rescue of splicing-mediated intron loss maximizes expression in lentiviral vectors containing the human ubiquitin C promoter. [PDF]
, 2014 Lentiviral vectors almost universally use heterologous internal promoters to express transgenes. One of the most commonly used promoter fragments is a 1.2-kb sequence from the human ubiquitin C (UBC) gene, encompassing the promoter, some enhancers, first
Cooper, Aaron R +3 more
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Distinct promoter elements mediate the co-operative effect of Brn-3a and p53 on the p21 promoter and their antagonism on the Bax promoter [PDF]
, 2002 Although the promoters of both the Bax and p21 genes are activated by p53, they differ in the effect on this activation of the POU family transcription factor Brn-3a. Thus, Brn-3a inhibits activation of the Bax promoter by p53 but enhances the ability of
Budhram-Mahadeo, VS +2 more
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Plasmalogens Mediate the Effect of Age on Bronchodilator Response in Individuals With Asthma
Frontiers in Medicine, 2020 Background: Asthma is known to display different phenotypes across the life-course, suggesting that age related changes are particularly relevant to understanding asthma pathogenesis and remission.
Joanne E. Sordillo +8 more
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In silico analysis of transcription factor binding sites in promoters of germin-like protein genes in rice [PDF]
Archives of Biological Sciences, 2016 Germins (GERs) and germin-like proteins (GLPs) play important roles in responses to various stresses; however, their function is still not fully understood. Significant insight into their function can be obtained by analyzing their promoters. In
Ilyas Muhammad +2 more
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Targets for the MalI repressor at the divergent Escherichia coliK-12malX-malI promoters [PDF]
, 2010 Random mutagenesis has been used to identify the target DNA sites for the MalI repressor at the divergent Escherichia coli K-12 malX-malI promoters. The malX promoter is repressed by MalI binding to a DNA site located from position -24 to position -9 ...
Barnard +22 more
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The July 1st Event and Beyond - Human Rights Situation in Mongolia
The Mongolian Journal of International Affairs, 2011 DOI: 10.5564/mjia.v0i15-16.36 Mongolian Journal of International Affairs No.15-16 2008-2009 pp.201 ...
B Munkhzorig
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Investigation of regulatory elements related to superoxide dismutase enzyme genes in wheat [PDF]
بیوتکنولوژی و بیوشیمی غلات, 2023 Introduction: Wheat, like other plants, uses antioxidant enzymes to deal with the high production of free oxygen radicals. Antioxidant enzymes are proteins or polypeptides that are activated in cooperation with cellular substances or mineral elements and
Armin Saed-Moucheshi, Hooshmand Safari
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Identification of Genes and inducible regulatory elements in response to heat and cold stresses in barley (Hordeum vulgare L.) [PDF]
بیوتکنولوژی و بیوشیمی غلات, 2022 Introduction: Barley (Hordeum vulgare), a member of the Poaceae family, is an important cereal grown in temperate climates worldwide. It was one of the first cultivated grains, especially in Eurasia 10,000 years ago. Globally, 70% of barley production is
Danial Kahrizi
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CRISPR/Cas9-based editing of a sensitive transcriptional regulatory element to achieve cell type-specific knockdown of the NEMO scaffold protein [PDF]
, 2018 The use of alternative promoters for the cell type-specific expression of a given mRNA/protein is a common cell strategy. NEMO is a scaffold protein required for canonical NF-κB signaling.
Babaei, Milad +7 more
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A nucleosome-free dG-dC-rich sequence element promotes constitutive transcription of the essential yeast RIO1 gene [PDF]
, 2003 RIO1 is an essential gene that encodes a protein serine kinase and is transcribed constitutively at a very low level. Transcriptional activation of RIO1 dispenses with a canonical TATA box as well as with classical transactivators or specific DNAbinding ...
Angermayr, M. +2 more
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