Results 21 to 30 of about 1,389,605 (343)

Plasmalogens Mediate the Effect of Age on Bronchodilator Response in Individuals With Asthma

open access: yesFrontiers in Medicine, 2020
Background: Asthma is known to display different phenotypes across the life-course, suggesting that age related changes are particularly relevant to understanding asthma pathogenesis and remission.
Joanne E. Sordillo   +8 more
doaj   +1 more source

In silico analysis of transcription factor binding sites in promoters of germin-like protein genes in rice [PDF]

open access: yesArchives of Biological Sciences, 2016
Germins (GERs) and germin-like proteins (GLPs) play important roles in responses to various stresses; however, their function is still not fully understood. Significant insight into their function can be obtained by analyzing their promoters. In
Ilyas Muhammad   +2 more
doaj   +1 more source

The July 1st Event and Beyond - Human Rights Situation in Mongolia

open access: yesThe Mongolian Journal of International Affairs, 2011
DOI: 10.5564/mjia.v0i15-16.36 Mongolian Journal of International Affairs No.15-16 2008-2009 pp.201 ...
B Munkhzorig
doaj   +1 more source

Founder mutation in the PMM2 promotor causes hyperinsulinemic hypoglycaemia/polycystic kidney disease (HIPKD)

open access: yesMolecular Genetics & Genomic Medicine, 2021
Background Polycystic kidney disease with hyperinsulinaemic hypoglycaemia (HIPKD) is a recently described disease caused by a single nucleotide variant, c.‐167G>T, in the promoter region of PMM2 (encoding phosphomannomutase 2), either in homozygosity or ...
Sumaya Islam   +9 more
doaj   +1 more source

Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors

open access: yesFrontiers in Neurology, 2022
Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases.
Bradley S. Hollidge   +9 more
doaj   +1 more source

Predicting bacterial promoter function and evolution from random sequences

open access: yeseLife, 2022
Predicting function from sequence is a central problem of biology. Currently, this is possible only locally in a narrow mutational neighborhood around a wildtype sequence rather than globally from any sequence. Using random mutant libraries, we developed
Mato Lagator   +6 more
doaj   +1 more source

MatInspector and beyond: promoter analysis based on transcription factor binding sites

open access: yesBioinform., 2005
MOTIVATION Promoter analysis is an essential step on the way to identify regulatory networks. A prerequisite for successful promoter analysis is the prediction of potential transcription factor binding sites (TFBS) with reasonable accuracy.
Cartharius K   +9 more
semanticscholar   +1 more source

Spatio-Temporal Modification of Lignin Biosynthesis in Plants: A Promising Strategy for Lignocellulose Improvement and Lignin Valorization

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Lignin is essential for plant growth, structural integrity, biotic/abiotic stress resistance, and water transport. Besides, lignin constitutes 10–30% of lignocellulosic biomass and is difficult to utilize for biofuel production. Over the past few decades,
Yongli Wang   +7 more
doaj   +1 more source

Methylation status of hypothalamic Mkrn3 promoter across puberty

open access: yesFrontiers in Endocrinology, 2023
Makorin RING finger protein 3 (MKRN3) is an important factor located on chromosome 15 in the imprinting region associated with Prader-Willi syndrome. Imprinted MKRN3 is expressed in hypothalamic regions essential for the onset of puberty and mutations in
Pavlos Fanis   +11 more
doaj   +1 more source

Engineering canker‐resistant plants through CRISPR/Cas9‐targeted editing of the susceptibility gene CsLOB1 promoter in citrus

open access: yesPlant Biotechnology Journal, 2017
Summary Citrus canker, caused by Xanthomonas citri subsp. citri (Xcc), is severely damaging to the global citrus industry. Targeted editing of host disease‐susceptibility genes represents an interesting and potentially durable alternative in plant ...
A. Peng   +7 more
semanticscholar   +1 more source

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