A nucleosome-free dG-dC-rich sequence element promotes constitutive transcription of the essential yeast RIO1 gene [PDF]
, 2003 RIO1 is an essential gene that encodes a protein serine kinase and is transcribed constitutively at a very low level. Transcriptional activation of RIO1 dispenses with a canonical TATA box as well as with classical transactivators or specific DNAbinding ...
Angermayr, M. +2 more
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CRISPR/Cas9-based editing of a sensitive transcriptional regulatory element to achieve cell type-specific knockdown of the NEMO scaffold protein [PDF]
, 2019 The use of alternative promoters for the cell type-specific expression of a given mRNA/protein is a common cell strategy. NEMO is a scaffold protein required for canonical NF-κB signaling.
Babaei, Milad +8 more
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In silico analysis of transcription factor binding sites in promoters of germin-like protein genes in rice [PDF]
Archives of Biological Sciences, 2016 Germins (GERs) and germin-like proteins (GLPs) play important roles in responses to various stresses; however, their function is still not fully understood. Significant insight into their function can be obtained by analyzing their promoters. In
Ilyas Muhammad +2 more
doaj +1 more source
ArgR is an essential local transcriptional regulator of the arcABC-operon in Streptococcus suis and crucial for biological fitness in acidic environment [PDF]
, 2011 Streptococcus suis is one of the most important pathogens in pigs and can also cause severe infections in humans. Despite its clinical relevance very little is known about the factors contributing to its virulence.
Benga, L. +6 more
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Quantitative Characterization of Combinatorial Transcriptional Control of the Lactose Operon of E. coli [PDF]
, 2007 It is the goal of systems biology to understand the behavior of the whole in terms of the knowledge of the parts. This is hard to achieve in many cases due to the difficulty of characterizing the many constituents and their complex web of interactions ...
Hwa, T. +3 more
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An investigation of herpes simplex virus promoter activity compatible with latency establishment reveals VP16-independent activation of immediate-early promoters in sensory neurones [PDF]
, 2011 Herpes simplex virus (HSV) type-1 establishes lifelong latency in sensory neurones and it is widely assumed that latency is the consequence of a failure to initiate virus immediate-early (IE) gene expression. However, using a Ore reporter mouse system in
Arthur, J. +6 more
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The Arabidopsis NADPH oxidases RbohD and RbohF display differential expression patterns and contributions during plant immunity [PDF]
, 2016 Plant NADPH oxidases, also known as respiratory burst oxidase homologues (RBOHs), produce reactive oxygen species (ROS) that perform a wide range of functions.
Antonio Molina +6 more
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Demonstration of the Presence of the "Deleted" MIR122 Gene in HepG2 Cells [PDF]
, 2015 MicroRNA 122 (miR-122) is highly expressed in the liver where it influences diverse biological processes and pathways, including hepatitis C virus replication and metabolism of iron and cholesterol.
Fei, Y +8 more
core +1 more source
Levulinic Acid-Inducible and Tunable Gene Expression System for Methylorubrum extorquens
Frontiers in Bioengineering and Biotechnology, 2021 Methylorubrum extorquens AM1 is an efficient platform strain possessing biotechnological potential in formate- and methanol-based single carbon (C1) bioeconomy.
Chandran Sathesh-Prabu +3 more
doaj +1 more source