Targets for the MalI repressor at the divergent Escherichia coliK-12malX-malI promoters [PDF]
, 2010 Random mutagenesis has been used to identify the target DNA sites for the MalI repressor at the divergent Escherichia coli K-12 malX-malI promoters. The malX promoter is repressed by MalI binding to a DNA site located from position -24 to position -9 ...
Barnard +22 more
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Plasmalogens Mediate the Effect of Age on Bronchodilator Response in Individuals With Asthma
Frontiers in Medicine, 2020 Background: Asthma is known to display different phenotypes across the life-course, suggesting that age related changes are particularly relevant to understanding asthma pathogenesis and remission.
Joanne E. Sordillo +8 more
doaj +1 more source
The July 1st Event and Beyond - Human Rights Situation in Mongolia
The Mongolian Journal of International Affairs, 2011 DOI: 10.5564/mjia.v0i15-16.36 Mongolian Journal of International Affairs No.15-16 2008-2009 pp.201 ...
B Munkhzorig
doaj +1 more source
Diagnostic Efficacy of SHOX2 Gene Hypermethylation for Lung Cancer: A Meta-Analysis
Chinese Journal of Lung Cancer, 2021 Background and objective Lung cancer is the most common malignant tumor in clinic. The prognosis of advanced patients is poor, and the 5-year survival rate is low. Therefore, early diagnosis becomes the key to improve the prognosis of patients. In recent
Qiang LIU +4 more
doaj +1 more source
CRISPR/Cas9-based editing of a sensitive transcriptional regulatory element to achieve cell type-specific knockdown of the NEMO scaffold protein [PDF]
, 2018 The use of alternative promoters for the cell type-specific expression of a given mRNA/protein is a common cell strategy. NEMO is a scaffold protein required for canonical NF-κB signaling.
Babaei, Milad +7 more
core +1 more source
CRISPR/Cas9-based editing of a sensitive transcriptional regulatory element to achieve cell type-specific knockdown of the NEMO scaffold protein [PDF]
, 2019 The use of alternative promoters for the cell type-specific expression of a given mRNA/protein is a common cell strategy. NEMO is a scaffold protein required for canonical NF-κB signaling.
Babaei, Milad +8 more
core +1 more source
Investigation of regulatory elements related to superoxide dismutase enzyme genes in wheat [PDF]
بیوتکنولوژی و بیوشیمی غلات, 2023 Introduction: Wheat, like other plants, uses antioxidant enzymes to deal with the high production of free oxygen radicals. Antioxidant enzymes are proteins or polypeptides that are activated in cooperation with cellular substances or mineral elements and
Armin Saed-Moucheshi, Hooshmand Safari
doaj +1 more source
Large-scale structural analysis of the core promoter in mammalian and plant genomes [PDF]
, 2005 DNA encodes at least two independent levels of functional information. The first level is for encoding proteins and sequence targets for DNA-binding factors, while the second one is contained in the physical and structural properties of the DNA molecule ...
Florquin, Kobe +4 more
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Identification of Genes and inducible regulatory elements in response to heat and cold stresses in barley (Hordeum vulgare L.) [PDF]
بیوتکنولوژی و بیوشیمی غلات, 2022 Introduction: Barley (Hordeum vulgare), a member of the Poaceae family, is an important cereal grown in temperate climates worldwide. It was one of the first cultivated grains, especially in Eurasia 10,000 years ago. Globally, 70% of barley production is
Danial Kahrizi
doaj +1 more source
Structural visualization of key steps in human transcription initiation. [PDF]
, 2013 Eukaryotic transcription initiation requires the assembly of general transcription factors into a pre-initiation complex that ensures the accurate loading of RNA polymerase II (Pol II) at the transcription start site. The molecular mechanism and function
Fang, Jie +3 more
core +1 more source