Results 41 to 50 of about 1,804,103 (360)

Myeloid zinc finger 1 (MZF1) is the most important transcriptional factor for porcine follistatin promoter

open access: yesJournal of Integrative Agriculture, 2015
Follistatin (FS) is a secreted protein, which was originally isolated from porcine follicular fluid. Expression of follistatin is tightly regulated during porcine growth and development.
Ya-meng SUN   +4 more
doaj   +1 more source

Founder mutation in the PMM2 promotor causes hyperinsulinemic hypoglycaemia/polycystic kidney disease (HIPKD)

open access: yesMolecular Genetics & Genomic Medicine, 2021
Background Polycystic kidney disease with hyperinsulinaemic hypoglycaemia (HIPKD) is a recently described disease caused by a single nucleotide variant, c.‐167G>T, in the promoter region of PMM2 (encoding phosphomannomutase 2), either in homozygosity or ...
Sumaya Islam   +9 more
doaj   +1 more source

Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors

open access: yesFrontiers in Neurology, 2022
Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases.
Bradley S. Hollidge   +9 more
doaj   +1 more source

The RNA Polymerase II Core Promoter in Drosophila. [PDF]

open access: yes, 2019
Transcription by RNA polymerase II initiates at the core promoter, which is sometimes referred to as the "gateway to transcription." Here, we describe the properties of the RNA polymerase II core promoter in Drosophila The core promoter is at a strategic
Kadonaga, James T   +2 more
core   +1 more source

Survivin a radiogenetic promoter for glioblastoma viral gene therapy independently from CArG motifs [PDF]

open access: yes, 2017
BACKGROUND: Radiogenetic therapy is a novel approach in the treatment of cancer, which employs genetic modification to alter the sensitivity of tumor cells to the effect of applied radiation.
Arafat WO   +16 more
core   +2 more sources

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard   +8 more
wiley   +1 more source

Isolation and molecular characterization of the FLOWERING LOCUS C gene promoter sequence in radish (Raphanus sativus L.)

open access: yesJournal of Integrative Agriculture, 2016
Both bolting and flowering times influence taproot and seed production in radish. FLOWERING LOCUS C (FLC) plays a key role in plant flowering by functioning as a repressor.
Yuan-yuan XU   +8 more
doaj   +1 more source

c-Maf Transcription Factor Regulates ADAMTS-12 Expression in Human Chondrogenic Cells. [PDF]

open access: yes, 2013
ObjectiveADAMTS (a disintegrin and metalloproteinase with thrombospondin type-1 motif) zinc metalloproteinases are important during the synthesis and breakdown of cartilage extracellular matrix.
Amanatullah, Derek F   +4 more
core   +2 more sources

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li   +6 more
wiley   +1 more source

Modeling and Simulation of CO2 Absorption into Promoted Aqueous Potassium Carbonate Solution in Industrial Scale Packed Column

open access: yesBulletin of Chemical Reaction Engineering & Catalysis, 2015
Carbon dioxide gas is a harmful impurity which is corrosive and it can damage the utilities and the piping system in industries. Chemical absorption is the most economical separation method which is widely applied in chemical industries for CO2 removal ...
Ali Altway   +7 more
doaj   +1 more source

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