Results 41 to 50 of about 1,392,700 (321)

Gateways to the FANTOM5 promoter level mammalian expression atlas

Genome Biology, 2015
The FANTOM5 project investigates transcription initiation activities in more than 1,000 human and mouse primary cells, cell lines and tissues using CAGE.
M. Lizio, J. Harshbarger, H. Shimoji, Jessica Severin, T. Kasukawa, S. Şahin, I. Abugessaisa, S. Fukuda, Fumi Hori, Sachi Ishikawa-Kato, C. Mungall, E. Arner, J. Baillie, N. Bertin, H. Bono, Michiel J. L. de Hoon, A. Diehl, Emmanuel Dimont, T. Freeman, Kaori Fujieda, Winston A Hide, R. Kaliyaperumal, Toshiaki Katayama, T. Lassmann, T. Meehan, Koro Nishikata, Hiromasa ONO, M. Rehli, A. Sandelin, E. Schultes, P. ’. ’t Hoen, Zuotian Tatum, Mark Thompson, Tetsuro Toyoda, Derek W. Wright, C. Daub, M. Itoh, Piero Carninci, Y. Hayashizaki, A. Forrest, H. Kawaji   +40 more
semanticscholar   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Isolation and Analysis of the Cppsy Gene and Promoter from Chlorella protothecoides CS-41

Marine Drugs, 2015
Phytoene synthase (PSY) catalyzes the condensation of two molecules of geranylgeranyl pyrophosphate to form phytoene, the first colorless carotene in the carotenoid biosynthesis pathway.
Meiya Li, Yan Cui, Zhibing Gan, Chunlei Shi, Xianming Shi   +4 more
doaj   +1 more source

اثر اصلاح کنند ه ها روی فعالیت کاتالیزورهای زیگلر-ناتا و خواص نهایی پلیمر در پلیمرشدن اولفین ها [PDF]

Baspārish, 2015
فعالیت کاتالیزور از مهم ترین پارامترها در فرایندهای پلیمرشدن است. برای یک سامانه کاتالیزوریفعالیت ممکن است به شرایط پلیمرشدن از قبیل دما و فشار وابسته باشد.
رضا بازوند, نعیمه بحری, مهدی نکومنش, حسین عابدینی   +3 more
doaj   +1 more source

MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease

New England Journal of Medicine, 2018
BACKGROUND Given the phenotypic similarities between rheumatoid arthritis (RA)–associated interstitial lung disease (ILD) (hereafter, RA‐ILD) and idiopathic pulmonary fibrosis, we hypothesized that the strongest risk factor for the development of ...
P. Juge, Joyce S. Lee, E. Ebstein, H. Furukawa, E. Dobrinskikh, S. Gazal, C. Kannengiesser, S. Ottaviani, S. Oka, S. Tohma, N. Tsuchiya, J. Rojas-Serrano, M. González-Pérez, M. Mejía, I. Buendía-Roldán, R. Falfán-Valencia, E. Ambrocio-Ortiz, E. Manali, S. Papiris, T. Karageorgas, D. Boumpas, K. Antoniou, C. V. van Moorsel, J. J. van der Vis, Y. D. de Man, J. Grutters, Yaping Wang, R. Borie, L. Wémeau-Stervinou, B. Wallaert, R. Flipo, H. Nunes, D. Valeyre, N. Saidenberg-Kermanac’h, M. Boissier, S. Marchand-Adam, A. Frazier, P. Richette, Y. Allanore, J. Sibilia, C. Dromer, C. Richez, T. Schaeverbeke, H. Lioté, G. Thabut, N. Nathan, S. Amselem, M. Soubrier, V. Cottin, A. Clément, K. Deane, A. Walts, T. Fingerlin, A. Fischer, J. Ryu, E. Matteson, T. Niewold, D. Assayag, A. Gross, P. Wolters, M. Schwarz, M. Holers, J. Solomon, T. Doyle, I. Rosas, C. Blauwendraat, M. Nalls, M. Debray, C. Boileau, B. Crestani, D. Schwartz, P. Dieudé   +71 more
semanticscholar   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Permutoric Promotion: Gliding Globs, Sliding Stones, and Colliding Coins [PDF]

arXiv, 2023
The first author recently introduced toric promotion, an operator that acts on the labelings of a graph $G$ and serves as a cyclic analogue of Sch\"utzenberger's promotion operator. Toric promotion is defined as the composition of certain toggle operators, listed in a natural cyclic order.
arxiv  

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Quantitative Analysis of the KSHV Transcriptome Following Primary Infection of Blood and Lymphatic Endothelial Cells

Pathogens, 2017
The transcriptome of the Kaposi’s sarcoma-associated herpesvirus (KSHV/HHV8) after primary latent infection of human blood (BEC), lymphatic (LEC) and immortalized (TIME) endothelial cells was analyzed using RNAseq, and compared to long-term latency in ...
A. Gregory Bruce, Serge Barcy, Terri DiMaio, Emilia Gan, H. Jacques Garrigues, Michael Lagunoff, Timothy M. Rose   +6 more
doaj   +1 more source

Dynamic delegation in promotion contests [PDF]

arXiv, 2023
I study how organizations assign tasks to identify the best candidate to promote among a pool of workers. Task allocation and workers' motivation interact through the organization's promotion decisions. The organization designs the workers' careers to both screen and develop talent.
arxiv