Results 71 to 80 of about 1,392,700 (321)
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
Frontiers in Genetics, 2020 The CD69 gene encodes a C-type lectin glycoprotein with immune regulatory properties which is expressed on the cell surfaces of all activated hematopoietic cells.
Jennifer Redondo-Antón +6 more
doaj +1 more source
Prediction of Prokaryotic and Eukaryotic Promoters Using Convolutional Deep Learning Neural Networks [PDF]
arXiv, 2016 Accurate computational identification of promoters remains a challenge as these key DNA regulatory regions have variable structures composed of functional motifs that provide gene specific initiation of transcription. In this paper we utilize Convolutional Neural Networks (CNN) to analyze sequence characteristics of prokaryotic and eukaryotic promoters
arxiv
Dynamical Analysis on Gene Activity in the Presence of Repressors and an Interfering Promoter [PDF]
, 2008 Transcription is regulated through interplay between transcription factors, an RNA polymerase(RNAP), and a promoter. Even for a simple repressive transcription factor that disturbs promoter activity at the initial binding of RNAP, its repression level is not determined solely by the dissociation constant of transcription factor but is sensitive to the ...
arxiv +1 more source
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
FEBS Letters, EarlyView.Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source
Studia Universitatis Babeş-Bolyai. Musica, 2013 Although identifying and defining texture as a specific sound organization in sound mass compositions comes about frequently in contemporary musicology, only a handful of researchers regard this as a tendency of what turns out to be a large number of ...
Andrei C. COZMA
doaj
Promotion on Generalized Oscillating Tableaux and Web Rotation [PDF]
arXiv, 2017 We introduce the notion of a generalized oscillating tableau and define a promotion operation on such tableaux that generalizes the classical promotion operation on standard Young tableaux. As our main application, we show that this promotion corresponds to rotation of the irreducible $A_2$-webs of G. Kuperberg.
arxiv
Model of Transcriptional Activation by MarA in Escherichia coli [PDF]
, 2009 We have developed a mathematical model of transcriptional activation by MarA in Escherichia coli, and used the model to analyze measurements of MarA-dependent activity of the marRAB, sodA, and micF promoters in mar-rob- cells. The model rationalizes an unexpected poor correlation between the mid-point of in vivo promoter activity profiles and in vitro ...
arxiv +1 more source
FEBS Letters, EarlyView.LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra +7 more
wiley +1 more source
E-Commerce Promotions Personalization via Online Multiple-Choice Knapsack with Uplift Modeling [PDF]
arXiv, 2021 Promotions and discounts are essential components of modern e-commerce platforms, where they are often used to incentivize customers towards purchase completion. Promotions also affect revenue and may incur a monetary loss that is often limited by a dedicated promotional budget. We study the Online Constrained Multiple-Choice Promotions Personalization
arxiv