BackgroundMorganella morganii is an emerging nosocomial opportunistic pathogen with increasing multidrug resistance. Antibiotic resistance, driven primarily by the horizontal transfer of resistance genes, has become a global health crisis.
Ye Yang+7 more
doaj +1 more source
How chromatin interactions shed light on interpreting non-coding genomic variants: opportunities and future direc-tions [PDF]
Genomic variants, including copy number variants (CNVs) and genome-wide associa-tion study (GWAS) single nucleotide polymorphisms (SNPs), represent structural alterations that influence genomic diversity and disease susceptibility. While coding region variants have been extensively studied, non-coding and regulatory variants present significant ...
arxiv
Genetic variations that predispose individuals to complex disorders, such as essential hypertension, may be found in gene coding regions, intronic regions or in gene promoter region.
O. A. Ershova, T. A. Bairova
doaj
Analysis of genetic polymorphism on the promoter region of a human liver carboxylesterase gene
Yasutsuna Sasaki+8 more
openaire +2 more sources
Systematic identification of disease-causing promoter and untranslated region variants in 8040 undiagnosed individuals with rare disease. [PDF]
Martin-Geary AC+24 more
europepmc +1 more source
Profiling conserved transcription factor binding motifs in Phaseolus vulgaris through comparative genomics. [PDF]
Kondratova L, Vallejos CE, Conesa A.
europepmc +1 more source
Drosophila architectural proteins M1BP and Opbp cooperatively form the active promoter of a ribosomal protein gene. [PDF]
Osadchiy I+7 more
europepmc +1 more source
Novel tools for genomic modification and heterologous gene expression in the phylum Planctomycetota. [PDF]
Haufschild T+5 more
europepmc +1 more source
Gene syntaxes modulate gene expression and circuit behavior on plasmids. [PDF]
Deng Y+3 more
europepmc +1 more source
Epigenome editing-mediated restoration of <i>FBN1</i> expression by demethylation of CpG island shore in porcine fibroblasts. [PDF]
Miyadai R+7 more
europepmc +1 more source