Results 91 to 100 of about 466,642 (309)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Adherence to Antiretroviral Therapy and Its Related Factors among HIV-Infected Patients: A Mixed-Methods Study [PDF]

open access: yesJournal of Midwifery & Reproductive Health
Background & aim: High levels of adherence to treatment among HIV patients as one of the sexually transmitted diseases (STD) are essential for promoting viral suppression and preventing drug resistance, but little is known about the factors that ...
Amin Ghanbari   +3 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Five steps to count the number of promoters harboring each 8-mer oligos within a selected group of promoters.

open access: yes, 2012
Five steps to count the number of promoters harboring each 8-mer oligos within a selected group of promoters.
Shisong Ma (31667)   +5 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Distinct classes of yeast promoters revealed by differential TAF recruitment

open access: yes, 2009
The transcription factor TFIID contains the TATA box binding protein (TBP) and multiple TBP-associated factors (TAFs). Here, the association of TFIID components with promoters that either are dependent on multiple TAFs (TAFdep) or have no apparent TAF ...
Bhaumik, Sukesh R.   +2 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Promoters Highlight More than Two Phenotypes of Diabetes

open access: yes, 2016
Promoters of genes associated with type 1 diabetes (T1D), Intermediary Diabetes Mellitus (IDM) and type 2 diabetes (T2D). T1D promoters (blue dots), T2D promoters (red dots) and promoters from genes associated with the “intermediary” phenotype (green ...
Paul Gagniuc (1818325)
core   +1 more source

PDC promoters in both species.

open access: yes, 2023
Expression of PDC1 and PDC5 promoters fused to YFP in high thiamine and thiamine starvation (no thiamine) in strains where the thiamine regulatory factors were deleted. (A) C. glabrata PDC promoters in S. cerevisiae strains. (B) S.
Cory A. Dottor (16052950)   +7 more
core   +1 more source

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