Results 91 to 100 of about 236,086 (290)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

PRONUNCIATION ZVUKOSPOLUK UKRAINIAN RESPONDENTS PMR: NORM AND DEVIATION

open access: yesЗаписки з українського мовознавства, 2015
The article attempts to identify, analyse and describe the deviations that appear as a result of rules violation, the attention is drawn to the typical mistakes of pronunciation, including pronunciation of hissing sounds before whistling and whistling ...
М. Л. Дружинець
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

AN ERROR ANALYSIS OF PHONEMESIN READING – ALOUD ACTIVITY \ud PRODUCED BY THE FIRSTSEMESTER STUDENTS OF ENGLISH \ud DEPARTMENT, MUHAMMADIYAH UNIVERSITY OF MALANG [PDF]

open access: yes, 2007
This study was conducted to analyze the error or phonemes in reading aloud activity produced by the first semester students of English Department of Muhammdiyah University of Malang. The design that the researcher used is descriptive qualitative research.
SUSILAWATI, FITRI
core  

Learning English pronunciation in and outside the classroom: Psychopedagogic considerations [PDF]

open access: yes, 2013
Udostępnienie publikacji Wydawnictwa Uniwersytetu Łódzkiego finansowane w ramach projektu „Doskonałość naukowa kluczem do doskonałości kształcenia”. Projekt realizowany jest ze środków Europejskiego Funduszu Społecznego w ramach Programu Operacyjnego ...
Majer, Halina
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

A PHONOLOGICAL ANALYSIS ON MADURESE ENGLISH STUDENTS’ PRONUNCIATION IN READING AN ENGLISH TEXT

open access: yesEducation Human and Development Journal, 2017
The study focuses on the analysis of phonology on Madurese English students‟ pronunciation in reading an English text. The writer identified kinds of English oscillographic pronunciation made by Madurese students in reading an English text, the ...
Tiyas Saputri
doaj   +1 more source

Language learning strategies : a study of strategies used by Japanese adults to learn English in New Zealand, with particular reference to perception and production of difficult phonemes : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Japanese at Massey University [PDF]

open access: yes, 2002
This thesis is an examination of strategies used for learning English by a number of Japanese adults in Wellington, New Zealand. It reports the participants' own perception of their selection and use of strategies, as well as quantitative and qualitative
Crawford, Masako
core  

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

Pronunciation learning attitudes: The case of EFL undergraduate students in Indonesia

open access: yesStudies in English Language and Education
A pronunciation-learning attitude is essential to help students improve their pronunciation proficiency. It is problematic when students do not care about learning proper pronunciation in the process of teaching and learning.
Toni Indrayadi   +3 more
doaj   +1 more source

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