Results 161 to 170 of about 1,984 (207)

Synthesis of propanolamine side chain deuterated propranolol, propranolol‐diol and 4‐hydroxypropranol

Journal of Labelled Compounds and Radiopharmaceuticals, 1978
AbstractSyntheses of 1‐(isopropylamino)‐3‐(1‐naphthyloxy)‐2‐propanol‐1,1,2,3,3‐d5 (1), 3‐(1‐naphthyloxy)‐1,2‐propanediol‐1,1,2,3,3‐d5 (2) and 1‐(isopropylamino)‐3‐(4‐hydroxy‐1‐naphthyloxy)‐2‐propanol‐1,1,2,3,3‐d5 (3) from epichlorohydrin‐d5 are described. Treatment of epichlorohydrin‐d5 with 1‐naphthol, in the presence of a catalytic amount of pyridine,
Richard B. Walker, Wendel L. Nelson
openaire   +2 more sources

Synthesis of a novel series of (aryloxy)propanolamines: new selective beta 2-blocking agents.

Journal of Medicinal Chemistry, 1984
A new family of beta-blocking drugs is described. The originality of the new molecules lies in their functionalized hydrophobic folded structure, the basic part of which contains a benzocyclobutene ring.
M. Carre, A. Youlassani, P. Caubére, A. Saint‐Aubin‐Floch, M. Blanc, C. Advenier   +5 more
semanticscholar   +1 more source

ChemInform Abstract: Stereoselective Synthesis of (S)‐Propanolamines: Liver Microsomes Mediated Opening of Epoxides with Arylamines.

ChemInform, 1992
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
M. V. Rao, Ahmed Kamal, A. R. Rao
openaire   +2 more sources

ChemInform Abstract: NEW CHIRAL AND ISOMERIC CYCLOPROPYL KETOXIME PROPANOLAMINE DERIVATIVES WITH POTENT β‐ADRENERGIC BLOCKING PROPERTIES

Chemischer Informationsdienst, 1985
AbstractIsomere Falintolol‐Derivate (V) und (VIII) sowie Analoga (X) und (XI) werden synthetisiert und als β‐Blocker untersucht.
Guy Andermann, Suman Rakhit, M. Bouzoubaa, G. Leclerc   +3 more
openaire   +4 more sources

ChemInform Abstract: SYNTHESIS AND PHARMACOLOGICAL STUDY OF 3‐PHENYL‐2‐PROPANOLAMINES

Chemischer Informationsdienst, 1979
AbstractAus Benzylchlormethyl‐keton (I) und den Grignard‐Reagenzien (II) werden die entsprechenden Chloralkohole (IIIa)‐(IIId) dargestellt und mit den sek. Aminen (IV) zu den entsprechenden Aminoalkoholen (Va)‐(Vd) umgesetzt.
J. Wepierre, C. Dupont, H. Galons, Jean-Francois Girardeau, C. Combet Farnoux, Marcel Miocque   +5 more
openaire   +2 more sources

Operationally simple, scalable synthesis of aryloxy propanolamines using glycerol as a green promoting media: Practical eco-friendly access to propranolol and atenolol

Sustainable Chemistry and Pharmacy, 2022
M. Saquib, M. F. Khan, Jaya Singh, Bhuttu Khan, Priti, Promod Kumar, M. K. Hussain   +6 more
semanticscholar   +1 more source

ChemInform Abstract: A New Series of Tricyclic (Aryloximino)propanolamines Displaying Very High Selective β2‐Blocking Properties.

, 1989
Brigitte Jamart‐Grégoire, P. Caubère, Marie Blanc, Jean Pierre Gnassounou, Charles Advenier   +4 more
openalex   +2 more sources

Pharmacokinetic Studies on Some Novel (2-Nitro-1-Imidazolyl) Propanolamine Radiosensitizers

1982
One area of current interest in radiosensitizer development is in the use of nitroimidazoles of a more polar nature than misonida-zole, combining the benefits of a shorter half-life, and thus reduced tissue exposure, which has been correlated with the neuropathy observed with misonidazole (1), while also minimising brain penetration through the blood ...
A. I. Minchinton, V.S. Randhawa, F.A. Stewart, Michael R.L. Stratford   +3 more
openaire   +2 more sources

ChemInform Abstract: Flavones. Part 1. Synthesis and Antihypertensive Activity of (3‐Phenylflavonoxy)propanolamines without β‐Adrenoceptor Antagonism.

, 1987
E. S. C. WU, T. E. Cole, T. A. Davidson, James C. Blosser, A R Borrelli, C. R. Kinsolving, T. E. Milgate, Robert B. Parker   +7 more
openalex   +2 more sources

β-Adrenoceptor agonists and antagonists: conformational analysis of the ethanolamine and propanolamine side-chain

Journal of Molecular Structure: THEOCHEM, 1993
Abstract The solid state conformations of the ethanolamine or propanolamine side-chain for a variety of β-adrenoceptor agonists and antagonists have been analysed and compared to those conformations determined in solution and theoretical gas states. For the arylethanolamine (AEA)-type compounds the ethanolamine side-chain conformations adopted in the
Dimitri Iakovidis, William J. Louis, Tracy L. Nero   +2 more
openaire   +2 more sources