Copper-catalysed selective hydroamination reactions of alkynes [PDF]
, 2014 The development of selective reactions that utilize easily available and abundant precursors for the efficient synthesis of amines is a long-standing goal of chemical research.
A Heutling +47 more
core +2 more sources
Sampling and analysis of airborne ammonia in workplaces of China
Journal of Occupational Health, Volume 62, Issue 1, January/December 2020., 2020 Abstract Objectives With the increasing demand for the detection of occupational hazard factors in workplaces, the national standard determination method for ammonia (sampling with absorbing solution‐analysis with Nessler reagent spectrophotometry) in the air of workplace presents many drawbacks during application in China.
Zhizhen Xu +4 more
wiley +1 more source
A chemo-centric view of human health and disease [PDF]
, 2017 Efforts to compile the phenotypic effects of drugs and environmental chemicals offer the opportunity to adopt a chemo-centric view of human health that does not require detailed mechanistic information. Here we consider thousands of chemicals and analyse
Aloy, Patrick, 1972- +2 more
core +1 more source
The role and source of 5′-deoxyadenosyl radical in a carbon skeleton rearrangement catalyzed by a plant enzyme [PDF]
, 1998 The last step in the biosynthesis of tropane alkaloids is the carbon skeleton rearrangement of littorine to hyoscyamine. The reaction is catalyzed by a cell-free extract prepared from cultured hairy roots of Datura stramonium.
Kervio, Eric +2 more
core +1 more source
A DFT study of the adsorption of deep eutectic solvents onto graphene and defective graphene nanoflakes [PDF]
, 2021 The interaction of four deep choline chloride-derived eutectic solvents (DESs) with both graphene nanoflakes (GNF) and its defective double-vacancy and Stone–Wales forms (DV-GNF and SW-GNF), was evaluated using density functional theory (DFT).
Ghenaatian, Hamid Reza +4 more
core +1 more source
The "etiome": identification and clustering of human disease etiological factors [PDF]
, 2009 BackgroundBoth genetic and environmental factors contribute to human diseases. Most common diseases are influenced by a large number of genetic and environmental factors, most of which individually have only a modest effect on the disease. Though genetic
Butte, Atul J +2 more
core +4 more sources
Сardioprotective agents with biaromatic structure. Part 4. Potassium hERG channels blockers and modulators [PDF]
, 2023 The hERG subtype potassium channel (Kv11.1) is one of the most important and one of the most studied biological targets for the creation of cardioprotective agents.
G. V. Mokrov
core +4 more sources
Flow cytometry, a powerful novel tool to rapidly assess bacterial viability in metal working fluids : proof-of-principle [PDF]
, 2019 Metalworking fluids (MWF) are water-or oil-based liquids to cool and lubricate tools, work pieces and machines, inhibit corrosion and remove swarf. One of the major problems in the MWF industry is bacterial growth as bacterial enzymes can cause MWF ...
Audenaert, Kris +5 more
core +3 more sources
Dearomative Cycloadditions Utilizing an Organic Photosensitizer: An Alternative to Iridium Catalysis [PDF]
, 2020 A highly efficient, cheap, and organic alternative to the commonly used iridium photosensitizer (Ir[dF(CF3)ppy](2)(dtbpy))PF6([Ir-F]) is presented for visible-light energy transfer catalysis. The organic dye 2CzPN surpasses [Ir-F] in selectivity while at
König, Burkhard, Rolka, Alessa B.
core +1 more source
Journal of Drug Delivery, Volume 2017, Issue 1, 2017., 2017 The crystallization of mefenamic acid in transdermal patch is a major problem that makes the patch unstable and decreases the drug release. The additive was used to inhibit crystallization of a mefenamic acid. Among the different types of additives, polyvinylpyrrolidone (PVP) K30 and PVP K90 were studied and found to be highly effective in inhibiting ...
Jirapornchai Suksaeree +3 more
wiley +1 more source