Results 41 to 50 of about 46,442 (255)

Propensity Score Weighting for Causal Inference with Clustered Data

Journal of Causal Inference, 2018
Propensity score weighting is a tool for causal inference to adjust for measured confounders in observational studies. In practice, data often present complex structures, such as clustering, which make propensity score modeling and estimation challenging.
Yang Shu
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

An Adjustment of Survey Data Using Propensity Score Weighting

Kodo Keiryogaku (The Japanese Journal of Behaviormetrics), 2007
This study proposes the adoption of a neural network as an alternative to logistic regression analysis, which is conventionally used to estimate the propensity score (Rosenbaum & Rubin, 1983). Moreover, covariates that are frequently obscured are presented.Considering the response pattern to a mail survey by random sampling as a criterion, we examined ...
Hideki TOYODA, Ikko KAWAHASHI, Kentaro NAKAMURA, Hotaka KATAHIRA   +3 more
openaire   +3 more sources

Association between cardiopulmonary bypass duration and early major adverse cardiovascular events after surgical repair of supravalvular aortic stenosis

Frontiers in Cardiovascular Medicine
BackgroundPatients who underwent surgical repair of supravalvular aortic stenosis (SVAS) are at high risk for postoperative major adverse cardiovascular events (MACE).
Simeng Zhang, Caiyi Wei, Bo Peng, Lizhi Lv, Fengbo Pei, Jianming Xia, Jun Yan, Jie Liu, Qiang Wang, Yi Shi   +9 more
doaj   +1 more source

Platelet parameters and risk of hypertension disorders of pregnancy: a propensity score adjusted analysis

Platelets, 2022
While the role of platelets in cardiovascular diseases among the general population has been widely reported, evidence is inconsistent regarding the association between platelet indices with hypertension in pregnant women.
Shanshan Lin, Lifang Zhang, Songying Shen, Dongmei Wei, Jinhua Lu, Xiaojuan Chen, Qiaozhu Chen, Xiaoyan Xia, Qiu Xiu   +8 more
doaj   +1 more source

Outcome-adjusted balance measure for generalized propensity score model selection

Journal of Statistical Planning and Inference, 2022
In this article, we propose the outcome-adjusted balance measure to perform model selection for the generalized propensity score (GPS), which serves as an essential component in estimation of the pairwise average treatment effects (ATEs) in observational studies with more than two treatment levels. The primary goal of the balance measure is to identify
Zhao, Honghe, Yang, Shu
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Double-adjustment in propensity score matching analysis: choosing a threshold for considering residual imbalance

BMC Medical Research Methodology, 2017
Background Double-adjustment can be used to remove confounding if imbalance exists after propensity score (PS) matching. However, it is not always possible to include all covariates in adjustment.
Tri-Long Nguyen, Gary S. Collins, Jessica Spence, Jean-Pierre Daurès, P. J. Devereaux, Paul Landais, Yannick Le Manach   +6 more
doaj   +1 more source