Results 51 to 60 of about 2,349,452 (293)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Factors used for propensity score adjustment.

, 2012
Factors used for propensity score adjustment.
Bryan Olin (125642), Mark Bunker (125646), Amara K. Jayewardene (125644), Francisco Moreno (125647)   +3 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The link between initial cardiac rhythm and survival outcomes in in-hospital cardiac arrest using propensity score matching, adjustment, and weighting

Scientific Reports
The association between the initial cardiac rhythm and short-term survival in patients with in-hospital cardiac arrest (IHCA) has not been extensively studied despite the fact that it is thought to be a prognostic factor in patients with out-of-hospital ...
Yong Han, Haofei Hu, Yuankai Shao, Zhe Deng, Dehong Liu   +4 more
doaj   +1 more source

Covariate adjusted nonparametric methods under propensity analysis

Frontiers in Applied Mathematics and Statistics
Propensity score is one of the most commonly used score functions in adjusting for covariates effect in statistical inference. It is important to understand the impact with propensity score in case some of the prespecified covariates are severely ...
Jiabu Ye, Dejian Lai
doaj   +1 more source

Propensity score matching with missing covariates via iterated, sequential multiple imputation

, 2011
In many observational studies, analysts estimate causal effects using propensity score matching. Estimation of propensity scores is complicated when covariate values intended for collection are in fact missing. To handle the missing data, one approach is
Reiter, Jerome P., Mitra, Robin
core   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Assessment of the E-value in the presence of bias amplification: a simulation study

BMC Medical Research Methodology
Background The E-value, a measure that has received recent attention in the comparative effectiveness literature, reports the minimum strength of association between an unmeasured confounder and the treatment and outcome that would explain away the ...
Eric Barrette, Lucas Higuera, Kael Wherry   +2 more
doaj   +1 more source

Estimating Causal Effect of Two-Dose COVID-19 Vaccination on Hospitalization

Journal of Biostatistics and Epidemiology
Objective: To estimate the effectiveness of two-dose COVID-19 vaccination in reducing hospitalization, accounting for complex confounding factors in observational studies.
Mohammad Taghi Shakeri, Mahboobeh Taherizadeh, Saeed Akhlaghi, Ehsan Mosa Farkhani   +3 more
doaj   +1 more source