Results 51 to 60 of about 1,792,800 (248)

Examining a causal effect of Gyeonggi innovation schools in Korea

open access: yesKEDI Journal of Educational Policy, 2017
This study evaluated the policy impact of the Gyeonggi innovation school movement. Of primary concern was whether or not the effect of the school reform observed from the survey data might be due to selection bias, that is, if the policy effect would be ...
Kyug-Seok Min
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Single-Inhaler Triple versus Dual Bronchodilator Therapy in COPD: Real-World Comparative Effectiveness and Safety

open access: yesInternational Journal of COPD, 2022
Samy Suissa,1,2 Sophie Dell’Aniello,1 Pierre Ernst1,2 1Centre for Clinical Epidemiology, Lady Davis Institute-Jewish General Hospital, Montreal, Quebec, Canada; 2Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec ...
Suissa S, Dell'Aniello S, Ernst P
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Real-World Effectiveness of Single-Inhaler Triple Therapy for COPD: Impact of Diabetes Comorbidity

open access: yesCOPD
Background Type 2 diabetes is a frequent comorbidity in chronic obstructive pulmonary disease (COPD) patients, with the GOLD treatment recommendations asserting that the presence of diabetes be disregarded in the choice of treatment.Methods In a cohort ...
Sophia Eilat-Tsanani   +2 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Prenatal WIC Participation Is Associated with Gestational Weight Gain: A Secondary Analysis of United States Birth Records

open access: yesCurrent Developments in Nutrition
Background: The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) provides breastfeeding support, nutritious supplemental foods, referrals to health care and social services, and nutrition counseling to eligible pregnant women.
Susana L Matias, Caitlin D French
doaj   +1 more source

What can functional transcranial Doppler ultrasonography reveal about the cerebral lateralization of writing

open access: yesFEBS Letters, EarlyView.
Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley   +1 more source

Augmentation of Propensity Scores for Medical Records-based Research [PDF]

open access: yes, 2013
Therapeutic research based on electronic medical records suffers from the possibility of various kinds of confounding. Over the past 30 years, propensity scores have increasingly been used to try to reduce this possibility.
Aickin, Mikel
core   +1 more source

Anforderung an die Daten für die Target-Trial-Emulation: Eine Diskussion unter Betrachtung von Patientenregistern

open access: yesGMS Medizinische Informatik, Biometrie und Epidemiologie
The article first considers basic requirements (e.g. recording of relevant confounders) and frequent sources of bias (e.g. immortal time bias) when using registry and other real-world data as the basis for comparative effectiveness analyses of treatments.
Mathes, Tim
doaj   +1 more source

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