Results 61 to 70 of about 1,792,800 (248)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Bone & Joint OpenAims: Hip and knee arthroplasty are among the most commonly performed surgical procedures worldwide but carry a risk of cardiovascular complications, including myocardial infarction (MI).
Ahmed Al-Saadawi +6 more
doaj +1 more source
BMC Medical Research Methodology, 2012 Background Propensity score (PS) methods are increasingly used, even when sample sizes are small or treatments are seldom used. However, the relative performance of the two mainly recommended PS methods, namely PS-matching or inverse probability of ...
Pirracchio Romain +2 more
doaj +1 more source
Distribution of propensity scores before and after propensity score matching.
, 2014 The propensity scores of unmatched patients were significantly different between the early- and late-start groups. The propensity scores of matched patients were almost the same between groups.
Nam-Ho Kim (277267) +10 more
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Frontiers in PharmacologyObjectiveThis study attempted to comprehensively assess the clinical outcomes of cases with progressive HCC (pHCC) undergoing treatment with TKI and ICI in conjunction with TACE, as compared to the combination of TKI with TACE alone.MethodsFrom March ...
Yanjun Shen +4 more
doaj +1 more source
Results for Roland scores stratified for percentiles of propensity scores.
, 2014 The first column shows the percentile intervals of propensity score. Subsequent columns show mean Roland scores within each percentile interval and for treated and untreated individuals at baseline and for the outcome at end of follow-up. The last column
Wilco C. Peul (406325) +3 more
core +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Education SciencesThis paper presents an analysis of survey data to examine the association between participating in one of the National Institute of Health’s (NIH) funded Building Infrastructure Leading to Diversity Initiative (BUILD) program and students’ intent to ...
Hector V. Ramos, Kim-Phuong L. Vu
doaj +1 more source