Results 61 to 70 of about 2,386,323 (274)

Existence and Uniqueness of Proper Scoring Rules

J. Mach. Learn. Res., 2015
To discuss the existence and uniqueness of proper scoring rules one needs to extend the associated entropy functions as sublinear functions to the conic hull of the prediction set. In some natural function spaces, such as the Lebesgue $L^p$-spaces over $\mathbb R^d$, the positive cones have empty interior.
openaire   +3 more sources

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

A Generalisation of the Signal‐to‐Noise Ratio Using Proper Scoring Rules

Meteorological Applications
A generalised concept of the signal‐to‐noise ratio (SNR) (or equivalently the ratio of predictable components, or RPC) is provided, based on proper scoring rules.
Jochen Bröcker, Eviatar Bach
doaj   +1 more source

Understanding norovirus reporting patterns in England: a mixed model approach

BMC Public Health, 2021
Background Norovirus has a higher level of under-reporting in England compared to other intestinal infectious agents such as Campylobacter or Salmonella, despite being recognised as the most common cause of gastroenteritis globally.
N. Ondrikova, H. E. Clough, N. A. Cunliffe, M. Iturriza-Gomara, R. Vivancos, J. P. Harris   +5 more
doaj   +1 more source

Localizing Strictly Proper Scoring Rules

Journal of the American Statistical Association
When comparing predictive distributions, forecasters are typically not equally interested in all regions of the outcome space. To address the demand for focused forecast evaluation, we propose a procedure to transform strictly proper scoring rules into their localized counterparts while preserving the score divergence and strict propriety.
Ramon F. A. de Punder, Cees G. H. Diks, Roger J. A. Laeven, Dick J. C. van Dijk   +3 more
openaire   +2 more sources

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

Spatio-temporal Modelling of H5N1 Avian Influenza Outbreaks in Europe (2021-2024) [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Highly Pathogenic Avian Influenza (HPAI), particularly the H5N1 strain, poses a significant ongoing threat to animal health, biodiversity and food security across Europe.
M. Jindal, M. Jindal, S. Lim, S. Lim, C. R. MacIntyre, C. R. MacIntyre   +5 more
doaj   +1 more source