Results 211 to 220 of about 10,092 (236)

Preparation of properdin by affinity chromatography

Immunochemistry, 1977
Abstract A new technique is described for the preparation of properdin by immune affinity chromatography. Anti-human properdin antibody was attached via its carboxyl groups to amine-substituted Sepharose 4B with the use of a water soluble carbodiimide.
James D. Ogle, J. Wesley Alexander, Cora K. Ogle   +2 more
openaire   +3 more sources

The Properdin System and Immunity

The Journal of Immunology, 1959
Summary A 100-fold purification of the third component of human complement (C′3) has been achieved, employing Fraction III-1 (Cohn Method 9) as starting material. The final product was electrophoretically heterogeneous but was free of the activities of other components of complement, properdin, plasmin and C′1-esterase.
Earl W Todd, Louis Pillemer, Irwin H Lepow   +2 more
openaire   +1 more source

Action of Tetracycline on the Level of Properdin

Nature, 1961
THE influence of antibiotics on the formation of antibodies has been studied by many authors. Recently, Patocka et al.1 published a paper describing the inhibitory effect of tetracycline on the formation of specific antibodies of various types in infections or after immunization with brucellae, the influenza virus and herpes in laboratory animals ...
Vl. Kubelka, M. Rybák
openaire   +3 more sources

Properdin

2018
Properdin, a 53 kDa glycoprotein, is a key positive regulator of the alternative pathway by significantly increasing the half-life of the C3 and C5 convertases. Properdin is also an initiator of the alternative pathway. Unlike most complement proteins, properdin is produced primarily by leucocytes rather than hepatocytes, and circulates at 4–25 μg/mL ...
openaire   +2 more sources

Solid phase radioimmunoassay of properdin

Immunochemistry, 1973
Abstract This report describes a solid phase radioimmunoassay for measuring properdin concentration, independent of other proteins in the properdin system. Polystyrene tubes are coated with mono-specific rabbit antiserum to human properdin. The competitive binding of increasing concentrations of unlabeled properdin (10–50 ng) and a constant amount of
Ira Goodkofsky, Joe O. Minta, Irwin H. Lepow   +2 more
openaire   +3 more sources

Properdin — Its Biologic Importance

New England Journal of Medicine, 1972
IN the classical complement system, complement action is initiated by immune complexes through the activation of C1, the first component of complement.
openaire   +3 more sources

Properdin Factor B

1984
The properdin factor B (BF) polymorphism comprises two common alleles, F and S; two less common alleles, Fl and SO.7 (previously termed SI); and several further rare alleles, described by Mauff et al. [1]. These electrophoretic variants have been used in traditional linkage analyses to map the structural gene coding for factor B between HLA-B and HLA ...
openaire   +2 more sources

CONCERNING THE NATURE OF THE PROPERDIN SYSTEM

Pediatrics, 1958
The properdin system, which is composed of properdin, magnesium and complement, has a variety of activities in vitro. Among these are the lysis of certain bacteria and abnormal erythrocytes, the inactivation of some viruses, and the ability to interact with polysaccharides from such diverse sources as bacteria, yeasts and normal or neoplastic mammalian
openaire   +3 more sources

Opsonic activity of properdin

Experientia, 1958
L'aggiunta di zimosano al siero normale di cavia ne diminuisce notevolmente il potere opsonico; l'aggiunta di properdina al siero inattivato con zimosano o col calore restaura interamente questo potere. La properdina usata da sola senza siero, non ha potere opsonico.
openaire   +2 more sources

PROPERDIN AND THE INACTIVATION OF VIRUSES

Annals of the New York Academy of Sciences, 1960
Harold S. Ginsberg, Ralph J. Wedgwood
openaire   +3 more sources