Results 61 to 70 of about 14,416 (178)

Highly accurate prophage island detection with PIDE

Genome Biology
As important mobile elements in prokaryotes, prophages shape the genomic context of their hosts and regulate the structure of bacterial populations. However, it is challenging to precisely identify prophages through computational methods.
Hongyan Gao, Bowen Li, Zihan Guo, Lei Zheng, Junnan Chen, Guanxiang Liang   +5 more
doaj   +1 more source

Systematic evaluation of phenotypic variations induced by prophages in a clinical isolate of Pseudomonas aeruginosa

mSystems
With the rise of antibiotic resistance, nosocomial infections caused by Pseudomonas aeruginosa present a significant challenge to healthcare systems. Prophages integrated into bacterial chromosomes play a key role in generating phenotypic and genotypic ...
Xiaoyu Li, Yang Tao, Bingrui Sui, DanDan Li, Lili Wang, Yumin Hou, Yongping Xu, Bijie Hu, Na Li, Demeng Tan   +9 more
doaj   +1 more source

Prevalence and Diversity Analysis of Candidate Prophages to Provide An Understanding on Their Roles in Bacillus Thuringiensis

Viruses, 2019
Bacillus thuringiensis (Bt) is widely used in producing biological insecticides. Phage contaminations during Bt fermentation can cause severe losses of yields.
Yajuan Fu, Yan Wu, Yihui Yuan, Meiying Gao   +3 more
doaj   +1 more source

IMACulate(DE3), an E. coli Strain for High Purity His‐Tagged Protein Purifications

Biotechnology and Bioengineering, Volume 123, Issue 8, Page 2127-2138, August 2026.
ABSTRACT Immobilised Metal Affinity Chromatography (IMAC) is widely used to purify his‐tagged recombinant proteins from Escherichia coli. However, endogenous contaminants with histidine clusters, such as GFAT and PDH E1 proteins, are often co‐purified with the target protein.
Jia Q. Truong, Dingyi Yu, Nan Hao, Chris Langendorf, Keith. E. Shearwin, Jessica K. Holien   +5 more
wiley   +1 more source

Prevalence, Antimicrobial Resistance, and Genetic Diversity of Non‐Typeable Streptococcus pneumoniae Carriage: A Systematic Review and Meta‐Analysis

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Non‐typeable Streptococcus pneumoniae (NT‐Sp) strains lack detectable capsules and are often missed by traditional serotyping. While associated primarily with asymptomatic carriage, NT‐Sp has emerged as a key player in antimicrobial resistance (AMR) gene dissemination and serotype replacement in the post‐vaccine era. This systematic
Robert K. Reeks, Onyansaniba K. Ntim, Eric S. Donkor   +2 more
wiley   +1 more source

Insights into diversity, host-range, and temporal stability of Bacteroides and Phocaeicola prophages

BMC Microbiology
Background Phages are critical components of the gut microbiome, influencing bacterial composition and function as predators, parasites, and modulators of bacterial phenotypes.
Nejc Stopnisek, Stina Hedžet, Tomaž Accetto, Maja Rupnik   +3 more
doaj   +1 more source

Regenerative Microbiology: Harnessing Bacterial Antagonism and Spatiotemporal Signaling for Diabetic Wound Repair

Smart Medicine, Volume 5, Issue 4, August 2026.
This review introduces “Regenerative Microbiology,” a framework that uses bacterial antagonism and phage therapy to address diabetic wound dysbiosis. By activating the p40/EGFR/PI3K axis and providing a vascular‐stratified precision roadmap, this approach shifts the paradigm from antimicrobial suppression to intelligent, microbe‐driven tissue ...
Sabri Saeed Sanabani
wiley   +1 more source

Closely Related Vibrio alginolyticus Strains Encode an Identical Repertoire of Caudovirales-Like Regions and Filamentous Phages

Viruses, 2020
Many filamentous vibriophages encode virulence genes that lead to the emergence of pathogenic bacteria. Most genomes of filamentous vibriophages characterized up until today were isolated from human pathogens.
Cynthia Maria Chibani, Robert Hertel, Michael Hoppert, Heiko Liesegang, Carolin Charlotte Wendling   +4 more
doaj   +1 more source

Mechanisms of Resistance, Insights From Case Reports, and Future Prospects in Mycobacteriophage Therapy

Journal of the Royal Society of New Zealand, Volume 56, Issue 4, August 2026.
Evolution of drug‐resistant mycobacterial infections warrants renewed efforts in identifying more efficient preventive and control strategies as well as alternative treatment options. Interest in phage therapy is regaining significant traction, especially in cases of failed conventional therapy.
Buhari Yusuf, Abdul Malik, Md Shah Alam, Lijie Li, Haftay Abraha Tadesse, Aweke Mulu Belachew, Cuiting Fang, Xirong Tian, Htin Lin Aung, Shuai Wang, Tianyu Zhang   +10 more
wiley   +1 more source

Recent Advances in the Molecular Mechanisms of Bacterial Anti‐Phage Defence Systems

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
Panoptes as an example for an antiphage system consists of OptS producing a cyclic dinucleotide that prevents activation of OptE, a transmembrane protein. Phage T4 infection introduces the sponge protein Acb2 that adsorbs the cyclic dinucleotide thus activating OptE which disrupts the cell membrane aborting phage infection.
Harald Brüssow
wiley   +1 more source