Results 91 to 100 of about 192,124 (377)

Weight Cycling Deregulates Eating Behavior in Mice via the Induction of Durable Gut Dysbiosis

open access: yesAdvanced Science, EarlyView.
Weight cycling in Humans is suspected to dysregulate eating behavior. Mice submitted to body weight cycling by alternating western‐type and regular chow diets display increased hedonic appetite when exposed to a palatable diet, reminiscent of binge‐eating episodes.
Mélanie Fouesnard   +13 more
wiley   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu   +11 more
wiley   +1 more source

Cutaneous lipogenesis: precursors utilized by guinea pig skin for lipid synthesis

open access: yesJournal of Lipid Research, 1971
Cutaneous lipogenesis was studied, using a guinea pig ear slice incubation technique, for the following precursors: acetate, propionate, butyrate, glucose, pyruvate, lactate, succinate, citrate, and selected amino acids.
VICTOR R. WHEATLEY   +5 more
doaj  

Unfolded protein response in gastric glandulocytes of rats with the pharmacological correction of type 2 diabetes

open access: yesGastroenterologìa, 2023
Background. The cellular and molecular mechanisms underlying gastrointestinal complications caused by type 2 diabetes mellitus (T2DM) may involve accumulation of misfolded proteins in the endoplasmic reticulum that disrupts protein homeostasis and ...
Y.G. Klys   +5 more
doaj   +1 more source

Formulation pre-screening of inhalation powders using computational atom-atom systematic search method [PDF]

open access: yes, 2014
This is an open access article published under a Creative Commons Attribution (CC-BY) License, which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.The synthonic modeling approach provides ...
Collins, Elizabeth   +10 more
core   +4 more sources

Autism in patients with propionic acidemia [PDF]

open access: yesMolecular Genetics and Metabolism, 2016
Certain inborn errors of metabolism have been suggested to increase the risk of autistic behavior. In an animal model, propionic acid ingestion triggered abnormal behavior resembling autism. So far only a few cases were reported with propionic acidemia and autistic features. From a series of twelve consecutively diagnosed cases with propionic acidemia,
Peter Witters   +13 more
openaire   +5 more sources

The Probiotic Parabacteroides johnsonii Ameliorates Metabolic Disorders Through Promoting BCAAs to BSCFAs Conversion

open access: yesAdvanced Science, EarlyView.
Clinical discovery and the proposed underlying mechanism by how P. johnsonii ameliorated metabolic disorders. Abstract The gut bacterium Parabacteroides spp. is increasingly recognized for its therapeutic potential in treating metabolic disorders. However, the role of Parabacteroides johnsonii in metabolic disorders is never reported.
Yimeng Chen   +9 more
wiley   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

open access: yesHepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández   +18 more
wiley   +1 more source

The Anti-Inflammatory and Antioxidant Effects of Sodium Propionate

open access: yesInternational Journal of Molecular Sciences, 2020
The major end-products of dietary fiber fermentation by gut microbiota are the short-chain fatty acids (SCFAs) acetate, propionate, and butyrate, which have been shown to modulate host metabolism via effects on metabolic pathways at different tissue ...
A. Filippone   +6 more
semanticscholar   +1 more source

Targeted Intervention Strategies for Maternal–Offspring Transmission of Christensenellaceae in Pigs via a Deep Learning Model

open access: yesAdvanced Science, EarlyView.
This study deciphers maternal‐driven microbial transmission in pigs using a deep learning model (maternal–offspring microbial transmission model), identifying Christensenellaceae R‐7 group as a key transmitted taxon. Filtered galacto‐oligosaccharides‐targeted Christensenellaceae R‐7 group alters offspring microbial functions via maternal ...
Haibo Shen   +9 more
wiley   +1 more source

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