Results 71 to 80 of about 179,024 (208)

Increase in colonic propionate as a method of preventing weight gain in adults aged 20–40 years: iPREVENT, a multicentre, double-blind, randomised, parallel-group trial

open access: yesEfficacy and Mechanism Evaluation
Background Overweight and obesity affect over 60% of the United Kingdom population and constitute a major risk factor for the development of comorbidities.
Gary Frost   +16 more
doaj   +1 more source

Enrichment and description of novel bacteria performing syntrophic propionate oxidation at high ammonia level.

open access: yesEnvironmental Microbiology, 2021
Inefficient syntrophic propionate degradation causes severe operating disturbances and reduces biogas productivity in many high-ammonia anaerobic digesters, but propionate-degrading microorganisms in these systems remain unknown.
Abhijeet Singh   +2 more
semanticscholar   +1 more source

Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier

open access: yesMicrobiome, 2017
Gut microbiota composition and function are symbiotically linked with host health and altered in metabolic, inflammatory and neurodegenerative disorders.
L. Hoyles   +6 more
semanticscholar   +1 more source

Key players in syntrophic propionate oxidation revealed by metagenome-assembled genomes from anaerobic digesters bioaugmented with propionic acid enriched microbial consortia

open access: yesFrontiers in Microbiology, 2022
Propionic acid (HPr) is frequently accumulated in anaerobic digesters due to its thermodynamically unfavorable degradation reaction. Here, we identify key players in HPr oxidation and organic overloading recovery from metagenome-assembled genomes (MAGs ...
Minjae Kim   +6 more
doaj   +1 more source

The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans

open access: yesScience Translational Medicine, 2019
Propionate activates the insulin counter-regulatory hormonal response in mice, resulting in insulin resistance and weight gain. A metabolic dysregulator in hiding Propionate is a short-chain fatty acid that is a commonly used food preservative. Tirosh et
A. Tirosh   +15 more
semanticscholar   +1 more source

Hyperglycinemia and Propionate Carboxylation

open access: yesThe Tohoku Journal of Experimental Medicine, 1970
The oxidation of propionate and methylmalonate was investigated in leukocytes from a patient with hyperglycinemia. It was found that the patient's leukocytes could oxidize both propionate and methylmalonate normally. These findings suggest that hyperglycinemia consists of primary type and secondary type.
TADA, KEIYA, ARAKAWA, TSUNEO
openaire   +3 more sources

Propionate catabolism by CD-associated adherent-invasive E. coli counteracts its anti-inflammatory effect

open access: yesGut Microbes, 2021
Crohn’s disease (CD) is a chronic and disabling inflammatory disorder of the gut that is profoundly influenced by intestinal microbiota composition, host genetics and environmental factors.
Allison Agus   +12 more
doaj   +1 more source

Effect of propionate on pyruvate metabolism in adipose tissue

open access: yesJournal of Lipid Research, 1967
Glyceride-glycerol formation in rat adipose tissue from pyruvate-2-14C is increased by fasting, while fatty acid synthesis is markedly depressed. In tissues of fasted animals glyceride-glycerol formation is maximal with concentrations of pyruvate ...
L. Reshef, J. Niv, B. Shapiro
doaj   +1 more source

Gut microbiota derived propionate regulates the expression of Reg3 mucosal lectins and ameliorates experimental colitis in mice.

open access: yesJournal of Crohn's & Colitis, 2020
BACKGROUND AND AIMS Reg3 lectins are antimicrobial peptides at mucosal surfaces of the gut, whose expression is regulated by pathogenic gut microbes via IL-22- or TLR signaling. In addition to antimicrobial effects, tissue protection is hypothesized, but
D. Bajic   +15 more
semanticscholar   +1 more source

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