Advanced NanoBiomed Research, EarlyView.Redox responsive mesoporous silica nanoparticles (MSNs) were engineered to deliver gemcitabine (Gem) and cisplatin (cisPt) at defined ratios to overcome chemoresistance in pancreatic ductal adenocarcinoma (PDAC). Optimized Gem MSNs and Gem cisPt MSNs enhanced cytotoxicity in murine and human Gem resistant models, with select formulations inducing ...
Tamanna Binte Huq +5 more
wiley +1 more source
Frontiers in Nutrition, 2018 Propionibacterium freudenreichii is a commercially relevant bacterium with probiotic potential. This bacterium can exert protective effects particularly against colorectal cancer (CRC), via the production of short chain fatty acids (SCFA), namely acetate
Marta R. Casanova +4 more
doaj +1 more source
A study to assess COPD Symptom-based Management and to Optimise treatment Strategy in Japan (COSMOS-J) based on GOLD 2011 [PDF]
, 2013 Background and objective: The Global initiative for chronic Obstructive Lung Disease(GOLD) Committee has proposed a chronic obstructive pulmonary disease (COPD) assessment framework focused on symptoms and on exacerbation risk. This study will evaluate a
Betsuyaku, T +7 more
core +1 more source
Frontiers in Nutrition, 2019 Consumption of sufficient quantities of oat products has been shown to reduce host cholesterol and thereby modulate cardiovascular disease risk. The effects are proposed to be mediated by the gel-forming properties of oat β-glucan which modulates host ...
Susan A. Joyce +6 more
doaj +1 more source
Thermophilic and mesophilic temperature phase anaerobic codigestion (TPAcD) compared with single-stage co-digestion of sewage sludge and sugar beet pulp lixiviation [PDF]
, 2016 The performance of temperature phase anaerobic co-digestion (TPAcD) for sewage sludge and sugar beet pulp lixiviation (using the process of exchanging the digesting substrate between spatially separated thermophilic and mesophilic digesters) was tested
Montañes Alonso, Rocío +2 more
core +1 more source
Microorganisms, 2020 The relationship between predominant physiological types of prokaryotes in marine sediments and propionate degradation through sulfate reduction, fermentation, and methanogenesis was studied in marine sediments.
Derya Ozuolmez +2 more
doaj +1 more source
Homoacetogenesis as an alternative hydrogen sink in the rumen : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Microbiology and Genetics at Massey University, Palmerston North, New Zealand. [PDF]
, 2016 Ruminant livestock contribute significantly to global greenhouse gas emissions. This is due to microorganisms, known as methanogens that generate methane from hydrogen and carbon dioxide during feed fermentation in the rumen.
Raju, Preeti
core
A novel class of CoA-transferase involved in short-chain fatty acid metabolism in butyrate-producing human colonic bacteria [PDF]
, 2005 Peer reviewedPublisher ...
Altschul +48 more
core +1 more source
Glucocorticoids for human skin: New aspects of the mechanism of action [PDF]
, 2005 Topical glucocorticoids have always been considered first-line drugs for inflammatory diseases of the skin and bronchial system. Applied systemically, glucocorticoids are used for severe inflammatory and immunological diseases and the inhibition of ...
Ahmed, M. +4 more
core +1 more source
Fecal propionate is a signature of insulin resistance in polycystic ovary syndrome
Frontiers in Cellular and Infection MicrobiologyObjectiveTo investigate the roles of fecal short-chain fatty acids (SCFAs) in polycystic ovary syndrome (PCOS).MethodsThe levels of SCFAs (acetate, propionate, and butyrate) in 83 patients with PCOS and 63 controls were measured, and their relationships ...
Sitong Dong +12 more
doaj +1 more source