Results 101 to 110 of about 89,583 (305)

A chronopharmacological comparison of ciprofol and propofol: focus on sedation and side effects

Frontiers in Molecular Neuroscience
Propofol is a commonly used intravenous anesthetic in clinical practice, while ciprofol, a propofol derivative, also targets GABAA receptors with enhanced anesthetic potency.
Xuehan Li, Xinqing Yang, Chen Chen, Ziqing Yu, Houping Wang, Ruixue Liu, Jianrong He, Bin Shu, Guangyou Duan, Erquan Zhang, Dapeng Ju, He Huang   +11 more
doaj   +1 more source

Cardiopulmonary Adverse Events of Remimazolam versus Propofol During Cervical Conization: A Randomized Controlled Trial

, 2023
Lini Wang,* Yi Wang,* Li Ma,* Yiting Wang, Xiaoxiao Mu, Zhaoxu Huang, Ziyu Zheng, Huang Nie Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, Fourth Military Medical University, Xi’an, People’s Republic of China&ast ...
Zheng Z, Ma L, Mu X, Huang Z, Wang Y, Nie H, Wang L   +6 more
core  

Pharmacokinetics of Intravenous Melatonin in Preschool‐Aged Pediatric Surgical Patients

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Melatonin may have several beneficial clinical effects in the perioperative setting. In children, it has been studied for preoperative anxiety, postoperative pain, and emergence delirium. Melatonin's pharmacokinetic profile is well‐known in adults, but data in young children are sparse.
Anne Louise de Barros Garioud, Arash de Barros Afshari, Lau Romlund Halgreen, Kristian Østergaard Nielsen, Lars Peter Kloster Andersen   +4 more
wiley   +1 more source

Median effective dose (ED50) of esketamine combined with different doses of propofol for children to inhibit the response to gastroscope insertion: a prospective dose–response clinical study

BMC Anesthesiology
Background This study aimed to evaluate whether combining esketamine with different doses of propofol could reduce drug requirements and minimize adverse effects in children undergoing gastroscopy.
Keqing Niu, Li Li, Xiaole Wu, Na Xia, Jianqiao Zhu   +4 more
doaj   +1 more source

Propofol differentially inhibits the release of glutamate, γ-aminobutyric acid and glycine in the spinal dorsal horn of rats [PDF]

Iranian Journal of Basic Medical Sciences, 2015
Objective(s): Propofol (2, 6-diisopropylphenol) is an intravenous anesthetic that is commonly used for the general anesthesia. It is well known that the spinal cord is one of the working targets of general anesthesia including propofol. However, there is
Jing Yang, Wei Wang, Zheng Yong, Weidong Mi, Hong Zhang   +4 more
doaj  

Propofol induced diverse and subtype-specific translocation of PKC families

Journal of Pharmacological Sciences, 2018
Propofol is the most commonly used anesthetic. Immunohistochemical studies have reported that propofol translocated protein kinase Cs (PKCs) in cardiomyocyte in a subtype-specific manner; however detailed features of the propofol-induced translocation of
Takeshi Miyahara, Naoko Adachi, Takahiro Seki, Izumi Hide, Shigeru Tanaka, Naoaki Saito, Masahiro Irifune, Norio Sakai   +7 more
doaj   +1 more source

Edema pulmonar debido a la inducción anestésica con propofol

, 2015
Pulmonary edema is infrequently reported after administration of propofol. This article describes pulmonary edema in a woman of 45 year old who presented for elective cholecystectomy for minimum access, under general anesthesia with propofol.
Santos Pérez, Luis Alberto
core   +1 more source

Intraoperative Cardiac Events During Pediatric Cardiac Magnetic Resonance Imaging Under Anesthesia: A Retrospective Cohort Study

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Children with congenital heart disease (CHD) frequently undergo cardiac magnetic resonance imaging (MRI) under anesthesia. Although these procedures lack surgical stimulus, patients remain physiologically vulnerable, and the incidence of perioperative cardiovascular instability in this setting is poorly defined.
Theodora Wingert, Justine Liang, Kelly Feldman, Amelie Delaporte, Christine Nguyen‐Buckley, Tristan Grogan, Alexandre Joosten, John Paul Finn, Ihab Ayad   +8 more
wiley   +1 more source

Motor Evoked Potentials Improve Targeting in Deep Brain Stimulation Surgery

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives One of the main challenges posed by the surgical deep brain stimulation (DBS) procedure is the successful targeting of the structures of interest and avoidance of side effects, especially in asleep surgery. Here, intraoperative motor evoked potentials (MEPs) might serve as tool to identify the pyramidal tract.
Petyo Nikolov, Verena Heil, Christian J. Hartmann, Nikola Ivanov, Philipp J. Slotty, Jan Vesper, Alfons Schnitzler, Stefan Jun Groiss   +7 more
wiley   +1 more source

Offset of pharmacodynamic effects and safety of remifentanil in intensive care unit patients with various degrees of renal impairment

, 2003
Introduction: This open label, multicentre study was conducted to assess the times to offset of the pharmacodynamic effects and the safety of remifentanil in patients with varying degrees of renal impairment requiring intensive care. Methods: A total of
Bach, Vagn, Bonde, Jan, Breen, Des, Kessler, Paul, Albrecht, Sven, Wilmer, Alexander, Bodenham, Andrew, Shaikh, Soraya   +7 more
core   +1 more source