Results 121 to 130 of about 218,446 (354)

Propofol-mediated loss of consciousness disrupts predictive routing and local field phase modulation of neural activity [PDF]

, 2023
Yihan Xiong, Jacob Donoghue, Mikael Lundqvist, Meredith Mahnke, Alex J. Major, Emery N. Brown, Earl K. Miller, André M. Bastos   +7 more
openalex   +1 more source

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

Mass Spectrometry Reviews, EarlyView.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo, Huiling Wang, Xiaolan Hu, Sasho Gligorovski, Xue Li, Pablo Sinues   +5 more
wiley   +1 more source

A chronopharmacological comparison of ciprofol and propofol: focus on sedation and side effects

Frontiers in Molecular Neuroscience
Propofol is a commonly used intravenous anesthetic in clinical practice, while ciprofol, a propofol derivative, also targets GABAA receptors with enhanced anesthetic potency.
Xuehan Li, Xinqing Yang, Chen Chen, Ziqing Yu, Houping Wang, Ruixue Liu, Jianrong He, Bin Shu, Guangyou Duan, Erquan Zhang, Dapeng Ju, He Huang   +11 more
doaj   +1 more source

External validation of the modified Marsh and Schnider models for medium-chain triglyceride propofol in target-controlled infusion anesthesia

BMC Anesthesiology
Background Propofol formulated with medium- and long-chain triglycerides (MCT/LCT propofol) has rapidly replaced propofol formulated with long-chain triglycerides (LCT propofol).
Seongheon Lee, Dongho Kang, Eunjin Song, Sungah Yoo, Seongwook Jeong   +4 more
doaj   +1 more source

Improved effect and mechanism of propofol on vascular hyporeactivity in septic rats

陆军军医大学学报
Objective To observe the improved effect of propofol on vascular hyporeactivity in septic rats and its underlying mechanism. Methods A total of 96 SD rats (12 weeks old, both genders, weighing 200~220 g) were randomly divided into sham group (n=16 ...
SUN Yue, ZHANG Jie, ZHANG Bindan
doaj   +1 more source

Propofol induced diverse and subtype-specific translocation of PKC families

Journal of Pharmacological Sciences, 2018
Propofol is the most commonly used anesthetic. Immunohistochemical studies have reported that propofol translocated protein kinase Cs (PKCs) in cardiomyocyte in a subtype-specific manner; however detailed features of the propofol-induced translocation of
Takeshi Miyahara, Naoko Adachi, Takahiro Seki, Izumi Hide, Shigeru Tanaka, Naoaki Saito, Masahiro Irifune, Norio Sakai   +7 more
doaj   +1 more source

Interacting Turing-Hopf Instabilities Drive Symmetry-Breaking Transitions in a Mean-Field Model of the Cortex: A Mechanism for the Slow Oscillation [PDF]

, 2013
Electrical recordings of brain activity during the transition from wake to anesthetic coma show temporal and spectral alterations that are correlated with gross changes in the underlying brain state. Entry into anesthetic unconsciousness is signposted by
Sleigh, James W., Steyn-Ross, D. Alistair, Steyn-Ross, Moira L.   +2 more
core   +3 more sources

Dexmedetomidine attenuates repeated propofol exposure-induced hippocampal apoptosis, PI3K/Akt/Gsk-3β signaling disruption, and juvenile cognitive deficits in neonatal rats

Molecular Medicine Reports, 2016
Propofol is one of the most widely used intravenous anesthetics. However, repeated exposure to propofol may cause neurodegeneration in the developing brain.
Yujie Wang, Chang-yi Wu, Bin Han, Fei Xu, Ming-feng Mao, Xiangyang Guo, Jun Wang   +6 more
semanticscholar   +1 more source

Polyelectromyography Under Propofol to Differentiate Functional from Idiopathic Dystonia: A Pilot Study

Movement Disorders, EarlyView.
Abstract Background Functional dystonia (FD) is one of the most diagnostically challenging functional movement disorders. Phenomenological features often lack specificity, as many are also observed in idiopathic dystonia (ID) and validated biomarkers to distinguish FD from ID are currently unavailable Objective To investigate potential differences in ...
Roberto Eleopra, Fabio Paio, Sara Rinaldo, Carla Carozzi, Amanda Oriana, Grazia Devigili, Luigi Michele Romito, Roberto Cilia, Nico Golfrè Andreasi, Gianfranco Gaudiano, Marta Corradi, Antonio Emanuele Elia, Fabiana Colucci, Arianna Braccia, Roberta Telese, Michele Tinazzi, Marco Gemma, Valentina Leta   +17 more
wiley   +1 more source

Anesthetic Choices and Postoperative Delirium Incidence: Propofol vs Sevoflurane [PDF]

, 2022
Jared Doan
openalex   +1 more source