Results 11 to 20 of about 152,792 (340)

Remimazolam tosilate compared with propofol for gastrointestinal endoscopy in elderly patients: a prospective, randomized and controlled study

BMC Anesthesiology, 2022
Background Remimazolam tosilate (HR7056, RT), a novel ultrashort-acting benzodiazepine, can be used for procedural sedation and general anaesthesia.
Jian-guo Guo, Yitao Qian, Xiaojin Zhang, S. Han, Qinye Shi, Jianhong Xu   +5 more
semanticscholar   +1 more source

Quality of Recovery After General Anesthesia with Remimazolam in Patients’ Undergoing Urologic Surgery: A Randomized Controlled Trial Comparing Remimazolam with Propofol

Drug Design, Development and Therapy, 2022
Background Remimazolam is a new medication with sedative and hypnotic effects. It has been demonstrated non-inferior to propofol in general anesthesia with regard to efficacy and safety. However, whether general anesthesia with remimazolam is better than
Y. Mao, Jin-He Guo, Jingjing Yuan, Erxian Zhao, Jianjun Yang   +4 more
semanticscholar   +1 more source

Use of remifentanil to reduce propofol injection pain and the required propofol dose in upper digestive tract endoscopy diagnostic tests [PDF]

Revista Brasileira de Anestesiologia, 2015
BACKGROUND AND OBJECTIVES: The introduction of propofol (2,6-diisopropylphenol) as a sedative agent has transformed the area of sedation for endoscopic procedures.
Gustavo Nadal Uliana, Elizabeth Milla Tambara, Giorgio Alfredo Pedroso Baretta   +2 more
doaj   +6 more sources

Efficacy and safety of subanesthetic doses of esketamine combined with propofol in painless gastrointestinal endoscopy: a prospective, double-blind, randomized controlled trial

BMC Gastroenterology, 2022
Background Painless gastrointestinal endoscopy is widely used for the diagnosis and treatment of digestive diseases. At present, propofol is commonly used to perform painless gastrointestinal endoscopy, but the high dose of propofol often leads to a ...
Yongtong Zhan, Shuqing Liang, Zecheng Yang, Qichen Luo, Shuaizhen Li, Jiamin Li, Zhaojia Liang, Yalan Li   +7 more
semanticscholar   +1 more source

Efficacy and safety of remimazolam besylate versus propofol during hysteroscopy: single-centre randomized controlled trial

BMC Anesthesiology, 2021
Background Remimazolam besylate is a newer benzodiazepine with characteristics of quick onset of effects, short maintenance and recovery times without accumulation in tissues.
Xiaoqiang Zhang, Shuang Li, J. Liu
semanticscholar   +1 more source

Postoperative Delirium after Dexmedetomidine versus Propofol Sedation in Healthy Older Adults Undergoing Orthopedic Lower Limb Surgery with Spinal Anesthesia: A Randomized Controlled Trial

Anesthesiology, 2022
Background: Delirium is a critical postoperative complication in older patients. Based on the hypothesis that intraoperative dexmedetomidine sedation would lower postoperative delirium than propofol sedation would, the authors compared the incidence of ...
Hyun-Jung Shin, Sun Woo Nam, H. Kim, Su-Hoon Yim, Sunghee Han, Jung-Won Hwang, S. Do, H. Na   +7 more
semanticscholar   +1 more source

Esketamine improves propofol-induced brain injury and cognitive impairment in rats

Translational Neuroscience, 2022
As an intravenous anesthetic, propofol has been indicated to induce neurotoxicity in both animal and human brains. It is of great significance to better understand the potential mechanism of propofol-induced neurotoxicity to eliminate the side effects of
Xu Guiping, Wang Yang, Chen Zhe, Zhang Yuxuan, Zhang Xuexue, Zhang Guichao   +5 more
doaj   +1 more source

Propofol Protects Myocardium From Ischemia/Reperfusion Injury by Inhibiting Ferroptosis Through the AKT/p53 Signaling Pathway

Frontiers in Pharmacology, 2022
The molecular mechanism underlying the protective role of propofol against myocardial ischemia/reperfusion (I/R) injury remains poorly understood. Previous studies have shown that ferroptosis is an imperative pathological process in myocardial I/R injury.
Shengqiang Li, Zhen Lei, Xiaomei Yang, Meng Zhao, Yonghao Hou, Di Wang, Shuhai Tang, Jingxin Li, JinGui Yu   +8 more
semanticscholar   +1 more source

Propofol: A Review of its Role in Pediatric Anesthesia and Sedation

CNS Drugs, 2015
Vidya Chidambaran
exaly   +2 more sources

The propofol-sparing effect of intravenous lidocaine in elderly patients undergoing colonoscopy: a randomized, double-blinded, controlled study

BMC Anesthesiology, 2020
Background Propofol provides a prominent sedation effect in colonoscopy. However, anesthesia and sedation induced with propofol in the elderly might result in cardiopulmonary complications, especially when it is combined with opoids in the regimen.
Mengmeng Chen, Yi Lu, Haoran Liu, Qingxia Fu, Jun Li, Junzheng Wu, Wangning Shangguan   +6 more
doaj   +1 more source