Propofol Inhibits Androgen Production in Rat Immature Leydig Cells
Frontiers in Pharmacology, 2019 Background: Propofol is a widely used anesthetic. Whether propofol inhibits androgen production by rat Leydig cells and the underlying mechanism remains unclear.
Yiyan Wang +8 more
doaj +1 more source
Non-equilibrium brain dynamics as a signature of consciousness [PDF]
Phys. Rev. E 104, 014411 (2021), 2020 The cognitive functions of human and non-human primates rely on the dynamic interplay of distributed neural assemblies. As such, it seems unlikely that cognition can be supported by macroscopic brain dynamics at the proximity of thermodynamic equilibrium.
arxiv +1 more source
Determination of propofol by GC/MS and fast GC/MS-TOF in two cases of poisoning [PDF]
, 2017 Two cases of suspected acute and lethal intoxication caused by propofol were delivered by the judicial authority to the Department of Sciences for Health Promotion and Mother-Child Care in Palermo, Sicily.
Argo A. +8 more
core +1 more source
An Analytic Method to Determine the Optimal Time for the Induction Phase of Anesthesia [PDF]
Axioms 12 (2023), no. 9, Art. 867, 15pp, 2023 We obtain an analytical solution for the time-optimal control problem in the induction phase of anesthesia. Our solution is shown to align numerically with the results obtained from the conventional shooting method. The induction phase of anesthesia relies on a pharmacokinetic/pharmacodynamic (PK/PD) model proposed by Bailey and Haddad in 2005 to ...
arxiv +1 more source
Journal of Mazandaran University of Medical Sciences, 2022 Background and purpose: Appropriate drug regimen during colonoscopy is one of the matters of concern in anesthesia. This study was conducted to compare the efficacy of propofol-ketamine combination and propofol-fentanyl in colonoscopy.
Mohammad Esmaeili +5 more
doaj
Safety and efficacy of a propofol and ketamine based procedural sedation protocol in children with cerebral palsy undergoing botulinum toxin A injections. [PDF]
, 2019 Background Pediatric patients with cerebral palsy (CP) often undergo intramuscular botulinum toxin (BoNT‐A) injections. These injections can be painful and may require procedural sedation.
Abu-Sultaneh, Samer +4 more
core +1 more source
Tracheal intubation without neuromuscular block in children
Indian Journal of Anaesthesia, 2010 Endotracheal intubation has been performed during the administration of Propofol anaesthesia without neuromuscular blockade. In the study, we have assessed tracheal intubating conditions and haemodynamic responses in children aged 4 to12 years by using ...
Safiya I Shaikh, Vijayalaxmi P Bellagali
doaj +1 more source
The cerebrovascular effects of adrenaline, noradrenaline and dopamine infusions under propofol and isoflurane anaesthesia in sheep [PDF]
, 2002 Publisher's copy made available with the permission of the publisher © Australian Society of AnaesthetistsInfusions of catecholamines are frequently administered to patients receiving propofol or isoflurane anaesthesia.
Fortin D. +5 more
core +2 more sources
Membrane Nanodomains Homeostasis During Propofol Anesthesia as Function of Dosage and Temperature [PDF]
, 2020 Some anesthetics bind and potentiate gamma-aminobutyric-acid-type receptors, but no universal mechanism for general anesthesia is known. Furthermore, often encountered complications such as anesthesia induced amnesia are not understood. General anesthetics are hydrophobic molecules easily dissolving into lipid bilayers.
arxiv +1 more source
Injection pain of propofol in children: A comparison of two formulations without added lidocaine
Journal of Anaesthesiology Clinical Pharmacology, 2012 Background: Propofol emulsion in medium and long-chain triglycerides (MCT/LCT) has been reported to cause less injection pain than other propofol solutions in adult studies.
Serbülent Gökhan Beyaz, Ali Eman
doaj +1 more source