Results 31 to 40 of about 152,792 (340)

Injection pain of propofol in children: A comparison of two formulations without added lidocaine

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2012
Background: Propofol emulsion in medium and long-chain triglycerides (MCT/LCT) has been reported to cause less injection pain than other propofol solutions in adult studies.
Serbülent Gökhan Beyaz, Ali Eman
doaj   +1 more source

Effects of propofol on the development of cancer in humans

open access: yesCell Proliferation, 2020
Cancer is one of most the significant threats to human health worldwide, and the primary method of treating solid tumours is surgery. Propofol, one of the most widely used intravenous anaesthetics in surgery, was found to be involved in many cancer ...
Yichi Xu   +4 more
semanticscholar   +1 more source

Influence of propofol‐based total intravenous anaesthesia on peri‐operative outcome measures: a narrative review

open access: yesAnaesthesia, 2020
Propofol‐based total intravenous anaesthesia is well known for its smooth, clear‐headed recovery and anti‐emetic properties, but there are also many lesser known beneficial properties that can potentially influence surgical outcome.
M. Irwin, C. Chung, K. Y. Ip, M. Wiles
semanticscholar   +1 more source

Effect of Intravenous Acetaminophen vs Placebo Combined With Propofol or Dexmedetomidine on Postoperative Delirium Among Older Patients Following Cardiac Surgery: The DEXACET Randomized Clinical Trial

open access: yesJournal of the American Medical Association (JAMA), 2019
Importance Postoperative delirium is common following cardiac surgery and may be affected by choice of analgesic and sedative. Objective To evaluate the effect of postoperative intravenous (IV) acetaminophen (paracetamol) vs placebo combined with IV ...
B. Subramaniam   +13 more
semanticscholar   +1 more source

Tracheal intubation without neuromuscular block in children

open access: yesIndian Journal of Anaesthesia, 2010
Endotracheal intubation has been performed during the administration of Propofol anaesthesia without neuromuscular blockade. In the study, we have assessed tracheal intubating conditions and haemodynamic responses in children aged 4 to12 years by using ...
Safiya I Shaikh, Vijayalaxmi P Bellagali
doaj   +1 more source

Association of Polymorphisms in Pharmacogenetic Candidate Genes with Propofol Susceptibility

open access: yesScientific Reports, 2017
Significant individual susceptibility to intravenous anesthetic propofol exists. The etiology of individual variability in the response to propofol may be influenced by genetic polymorphisms in metabolic and functional pathways.
Qi Zhong   +4 more
doaj   +1 more source

Effects of different rates of propofol with or without S-ketamine on ventricular function in healthy cats – a randomized study

open access: yesFrontiers in Veterinary Science, 2023
Propofol is used for anesthetic induction in cats and procedural sedation in countries where alfaxalone is not available. Studies have reported propofol-related effects in echocardiography variables in dogs and humans.
Sabrine Marangoni   +7 more
doaj   +1 more source

Central depressant effects and toxicity of propofol in chicks

open access: yesToxicology Reports, 2014
Propofol is an ultra-short acting anesthetic agent. The information on the pharmacological and toxicological effects of propofol in the chicken is rather limited.
A.S. Naser, F.K. Mohammad
doaj   +1 more source

Disturbance of Key Cellular Subproteomes upon Propofol Treatment Is Associated with Increased Permeability of the Blood-Brain Barrier

open access: yesProteomes, 2022
Background: Propofol is a short-acting anesthetic, which is often used for induction and maintenance of general anesthesia, sedation for mechanically ventilated adults and procedural sedation.
Timo Längrich   +6 more
doaj   +1 more source

Propofol induces nuclear localization of Nrf2 under conditions of oxidative stress in cardiac H9c2 cells. [PDF]

open access: yesPLoS ONE, 2018
Oxidative stress contributes to myocardial ischemia-reperfusion injury, which causes cardiomyocyte death and precipitate life-threatening heart failure. Propofol has been proposed to protect cells or tissues against oxidative stress.
Takeaki Shinjo   +10 more
doaj   +1 more source

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