Results 31 to 40 of about 218,446 (354)

Comparison of the qCON and qNOX indices for the assessment of unconsciousness level and noxious stimulation response during surgery [PDF]

open access: yes, 2016
The objective of this work is to compare the performances of two electroencephalogram based indices for detecting loss of consciousness and loss of response to nociceptive stimulation.
Agustí, Mercé   +8 more
core   +2 more sources

On the role of the corpus callosum in interhemispheric functional connectivity in humans [PDF]

open access: yes, 2017
Resting state functional connectivity is defined in terms of temporal correlations between physiologic signals, most commonly studied using functional magnetic resonance imaging. Major features of functional connectivity correspond to structural (axonal)
Hacker, Carl D.   +8 more
core   +2 more sources

Association of Polymorphisms in Pharmacogenetic Candidate Genes with Propofol Susceptibility

open access: yesScientific Reports, 2017
Significant individual susceptibility to intravenous anesthetic propofol exists. The etiology of individual variability in the response to propofol may be influenced by genetic polymorphisms in metabolic and functional pathways.
Qi Zhong   +4 more
doaj   +1 more source

Propofol Induction Reduces the Capacity for Neural Information Integration: Implications for the Mechanism of Consciousness and General Anesthesia [PDF]

open access: yes, 2008
The cognitive unbinding paradigm suggests that the synthesis of cognitive information is attenuated by general anesthesia. Here, we investigated the functional organization of brain activities in the conscious and anesthetized states, based on ...
Byung-Moon Choi   +4 more
core   +2 more sources

Effect of Intravenous Acetaminophen vs Placebo Combined With Propofol or Dexmedetomidine on Postoperative Delirium Among Older Patients Following Cardiac Surgery: The DEXACET Randomized Clinical Trial

open access: yesJournal of the American Medical Association (JAMA), 2019
Importance Postoperative delirium is common following cardiac surgery and may be affected by choice of analgesic and sedative. Objective To evaluate the effect of postoperative intravenous (IV) acetaminophen (paracetamol) vs placebo combined with IV ...
B. Subramaniam   +13 more
semanticscholar   +1 more source

Effects of different rates of propofol with or without S-ketamine on ventricular function in healthy cats – a randomized study

open access: yesFrontiers in Veterinary Science, 2023
Propofol is used for anesthetic induction in cats and procedural sedation in countries where alfaxalone is not available. Studies have reported propofol-related effects in echocardiography variables in dogs and humans.
Sabrine Marangoni   +7 more
doaj   +1 more source

Direct Current Auditory Evoked Potentials During Wakefulness, Anesthesia, and Emergence from Anesthesia [PDF]

open access: yes, 2001
Direct current auditory evoked potentials (DC-AEPs) are a sensitive indicator of depth of anesthesia in ani-mals. However, they have never been investigated in humans. To assess the potential usefulness of DC-AEPs as an indicator of anesthesia in humans,
Bauer, Herbert   +5 more
core   +1 more source

Propofol induces nuclear localization of Nrf2 under conditions of oxidative stress in cardiac H9c2 cells. [PDF]

open access: yesPLoS ONE, 2018
Oxidative stress contributes to myocardial ischemia-reperfusion injury, which causes cardiomyocyte death and precipitate life-threatening heart failure. Propofol has been proposed to protect cells or tissues against oxidative stress.
Takeaki Shinjo   +10 more
doaj   +1 more source

Disturbance of Key Cellular Subproteomes upon Propofol Treatment Is Associated with Increased Permeability of the Blood-Brain Barrier

open access: yesProteomes, 2022
Background: Propofol is a short-acting anesthetic, which is often used for induction and maintenance of general anesthesia, sedation for mechanically ventilated adults and procedural sedation.
Timo Längrich   +6 more
doaj   +1 more source

Central depressant effects and toxicity of propofol in chicks

open access: yesToxicology Reports, 2014
Propofol is an ultra-short acting anesthetic agent. The information on the pharmacological and toxicological effects of propofol in the chicken is rather limited.
A.S. Naser, F.K. Mohammad
doaj   +1 more source

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