Results 71 to 80 of about 1,821,882 (341)
Testing and Confidence Intervals for High Dimensional Proportional Hazards Model [PDF]
Journal of The Royal Statistical Society Series B-statistical Methodology, 2014 The paper considers the problem of hypothesis testing and confidence intervals in high dimensional proportional hazards models. Motivated by a geometric projection principle, we propose a unified likelihood ratio inferential framework, including score ...
Ethan X. Fang, Y. Ning, Han Liu
semanticscholar +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
On hazard ratio estimators by proportional hazards models in matched-pair cohort studies
Emerging Themes in Epidemiology, 2017 BackgroundIn matched-pair cohort studies with censored events, the hazard ratio (HR) may be of main interest. However, it is lesser known in epidemiologic literature that the partial maximum likelihood estimator of a common HR conditional on matched ...
T. Shinozaki +2 more
semanticscholar +1 more source
A simple test of the proportional hazards assumption [PDF]
Biometrika, 1987 A new test of the proportional hazards assumption for two-sample censored data is presented. The test is based on a comparison of different generalized rank estimators of the relative risk. Asymptotic normality and consistency against alternatives with monotone hazard ratio are shown and relationships to other proposals are pointed out.
Gill, Richard, Schumacher, Martin
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Time to Default in Credit Scoring Using Survival Analysis [PDF]
Management and Economics Review, 2017 Credit risk assesment has been dominated by logistic and probit regression techniques. As the use of credit scoring has expanded over the past 20 years, concerns have been raised about whether its use may unfairly affect minorities. The aim of this paper
Ana Maria SANDICA, Monica DUDIAN
doaj
Comparison of regression imputation methods of baseline covariates that predict survival outcomes
Journal of Clinical and Translational Science, 2021 Introduction: Missing data are inevitable in medical research and appropriate handling of missing data is critical for statistical estimation and making inferences.
Nicole Solomon +2 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Comparison of methods for estimating the attributable risk in the context of survival analysis
BMC Medical Research Methodology, 2017 Background The attributable risk (AR) measures the proportion of disease cases that can be attributed to an exposure in the population. Several definitions and estimation methods have been proposed for survival data.
Malamine Gassama +3 more
doaj +1 more source
Journal of Clinical Epidemiology, 1995 The analytical effect of the number of events per variable (EPV) in a proportional hazards regression analysis was evaluated using Monte Carlo simulation techniques for data from a randomized trial containing 673 patients and 252 deaths, in which seven ...
P. Peduzzi +3 more
semanticscholar +1 more source