Results 71 to 80 of about 656,427 (214)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Cox Proportional Hazards Data.
, 2013 Cox Proportional Hazards Data.
Alexander Brawanski (322625) +9 more
core +1 more source
E-Jurnal Matematika, 2013 Survival analysis is a statistical method that accommodates the collection of censored data. One of popular method in survival analysis is the Cox Proportional Hazard Regression.
I GEDE ARI SUDANA +2 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
The proportional representation review.
, 1893 Continued as a department of: Direct legislation record and the proportional representation review."A quarterly magazine, devoted to the reformation of the method of electing representatives."Title from cover.Mode of access: Internet.Revived and absorbed
American Proportional Representation League.
core
Contemporary Clinical Trials Communications, 2015 The semi-parametric proportional hazards model is widely adopted in randomized clinical trials with time-to-event outcomes, and the log-rank test is frequently used to detect a potential treatment effect.
Pei He, Zheng Su
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Regularization Paths for Cox's Proportional Hazards Model via Coordinate Descent [PDF]
We introduce a pathwise algorithm for the Cox proportional hazards model, regularized by convex combinations of l_1 and l_2 penalties (elastic net). Our algorithm fits via cyclical coordinate descent, and employs warm starts to find a solution along a ...
Trevor Hastie +3 more
core
Univariate Cox proportional hazards analysis.
, 2015 a Hazard ratio adjusted for age and gender. In bold variables with p < 0.2 implemented in the multivariate cox proportional hazards analysis.Univariate Cox proportional hazards analysis.
Manon Barutaut (704548) +10 more
core +1 more source
ANALYSIS MULTILEVEL SURVIVAL DATA USING COVARIATE-ADJUSTED FRAILTY PROPORTIONAL HAZARDS MODEL
Media StatistikaMultilevel survival data is time-to-event data with a hierarchical or nested structure. This study aims to model the data using the Covariate-Adjusted Frailty Proportional Hazards method, which is an extension of the Cox proportional hazards model with ...
Krismona Sandelvia +1 more
doaj +1 more source