Results 61 to 70 of about 375,990 (324)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

A disposição física da Sala de Audiências: a proximidade dos Membros do Poder Judiciário e do Ministério Público e seus reflexos sobre o devido Processo Legal

open access: yesRevista Interdisciplinar de Direito, 2015
The present study seeks to analyze the unconstitutionality of Article 18, I, “a” of Supplementary Law nº 75/93 and Article 41, Clause XI of the Law 8.625 / 1993.
Márcia Berião César
doaj  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Improvment of Clothes Fit for Different Female Bodies

open access: yesAUTEX Research Journal, 2017
The factors influencing for fit and suit of women’s clothing have been studied. The main reason of misfit is the nonconformity between the front and back width of pattern block, the corresponding body sizes taken across the hipline, and the textile ...
Surikova Olga V.   +2 more
doaj   +1 more source

Gesture enhancement of a virtual tutor via investigating human tutor discursive strategies: Forms and functions for proportions [PDF]

open access: yes, 2014
We examine expert human mathematics-tutor gestures in the context of an interactive design for proportionality in order to design a virtual pedagogical agent.
Abrahamson, D, Flood, VJ, Schneider, A
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Criminal Intelligence and the Privacy of Human Life

open access: yesTeisė, 2019
The article analyzes the problematic aspects of applicating the provisions of the Criminal Intelligence Act to the disclosure criminal offences. The author goes deeper into how much of the means used by criminal intelligence can legitimately penetrate ...
Aurelijus Gutauskas
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Piecewise straightening and Lipschitz simplicial volume [PDF]

open access: yes, 2015
We study the Lipschitz simplicial volume, which is a metric version of the simplicial volume. We introduce the piecewise straightening procedure for singular chains, which allows us to generalize the proportionality principle and the product inequality ...
Strzałkowski, Karol
core  

Hesitant Fuzzy SWARA-Complex Proportional Assessment Approach for Sustainable Supplier Selection (HF-SWARA-COPRAS) [PDF]

open access: gold, 2020
Pratibha Rani   +6 more
openalex   +1 more source

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