Results 71 to 80 of about 375,990 (324)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

Zasada proporcjonalności a ograniczenia reklamy w uchwałach krajobrazowych

open access: yesActa Iuris Stetinensis, 2019
The article analyzes the importance of the constitutional principle of proportionality in the assessment of the legality of the restrictions on outdoor advertising introduced under the Communal Landscape Acts.
Andrzej Nałęcz
doaj   +1 more source

Fair and Square: Cake-Cutting in Two Dimensions

open access: yes, 2017
We consider the classic problem of fairly dividing a heterogeneous good ("cake") among several agents with different valuations. Classic cake-cutting procedures either allocate each agent a collection of disconnected pieces, or assume that the cake is a ...
Aumann, Yonatan   +3 more
core   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

Conclusiones de la Abogado General Kokott en los asuntos contra la Directiva de los productos del tabaco: ¿Un paso al frente hacia una verdadera política de salud de la Unión Europea?

open access: yesEuropean Papers, 2016
(Series Information) European Papers - A Journal on Law and Integration, 2016 1(1), 287-297 | European Forum Insight of 16 April 2016 | (Table of Contents) I. Introducción. - II. Los hechos. - III. Apreciación jurídica de la Abogado General.
Elisabet Ruiz Cairó
doaj   +1 more source

Natural Resource Distribution and Multiple Forms of Civil War [PDF]

open access: yes
We examine how natural resource location, rent sharing and fighting capacities of different groups matter for ethnic conflict. A new type of bargaining failure due to multiple types of potential con.icts (and hence multiple threat points) is identified ...
Dominic Rohner, Massimo Morelli
core  

Scaling of variables and the relation between noncommutative parameters in Noncommutative Quantum Mechanics

open access: yes, 2005
We consider Noncommutative Quantum Mechanics with phase space noncommutativity. In particular, we show that a scaling of variables leaves the noncommutative algebra invariant, so that only the self-consistent effective parameters of the model are ...
C. M. L. DE ARAGÃO   +6 more
core   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

On the investment implications of bankruptcy laws [PDF]

open access: yes, 2010
Axiomatic analysis of bankruptcy problems reveals three major principles: (i) proportionality (PRO), (ii) equal awards (EA), and (iii) equal losses (EL). However, most real life bankruptcy procedures implement only the proportionality principle.
Kıbrıs, Arzu   +3 more
core  

Stringy Symmetries and Their High-energy Limits

open access: yes, 2005
We derive stringy symmetries with conserved charges of arbitrarily high spins from the decoupling of two types of zero-norm states in the old covariant first quantized (OCFQ) spectrum of open bosonic string.
Chan   +24 more
core   +1 more source

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