Vascular Health and Risk Management, 2017 Alberico Luigi Catapano,1,2 Angela Pirillo,1,2 Giuseppe Danilo Norata1,3,4 1Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 2IRCCS Multimedica Hospital, Sesto San Giovanni, 3Center for the Study of ...
Catapano AL, Pirillo A, Norata GD
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Gene expression of prohormone and proprotein convertases in the rat CNS: a comparative in situ hybridization analysis [PDF]
, 1993 MK Schafer +5 more
openalex +1 more source
cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases. [PDF]
, 1996 Nabil G. Seidah +7 more
openalex +1 more source
Proprotein convertase expression and localization in epidermis: evidence for multiple roles and substrates [PDF]
, 2001 David J. Pearton +5 more
openalex +2 more sources
Polyphenols with indirect proprotein convertase inhibitory activity
International Journal of Oncology, 2013 Polyphenols, a class of natural products, have been shown to exhibit cancer protective properties. Proprotein convertases form a family of mammalian subtilisin-like serine endoproteases. Increased expression of these enzymes has been associated with numerous pathologies including cancer.
Wim J.M. Van de Ven +2 more
openaire +4 more sources
The isoforms of proprotein convertase PC5 are sorted to different subcellular compartments. [PDF]
, 1996 Isabelle De Bie +6 more
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International Journal of Biological Sciences, 2010 Proprotein convertases are enzymes that proteolytically cleave protein precursors in the secretory pathway to yield functional proteins. Seven mammalian subtilisin/Kex2p-like proprotein convertases have been identified: furin, PC1, PC2, PC4, PACE4, PC5 ...
Sun Tian, Wu Jianhua
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Effects of PCSK9 Targeting: Alleviating Oxidation, Inflammation, and Atherosclerosis [PDF]
Characterized as a chronic inflammatory disease of the large arteries, atherosclerosis is the primary cause of cardiovascular disease, the leading contributor of morbidity and mortality worldwide.
Diaba‐Nuhoho, Patrick +4 more
core +2 more sources
The Yeast Proprotein Convertase Encoded by YAP3 Is a Glycophosphatidylinositol-anchored Protein That Localizes to the Plasma Membrane [PDF]
, 1995 Josée Ash +4 more
openalex +1 more source
Secreted PCSK9 downregulates low density lipoprotein receptor through receptor-mediated endocytosis
Journal of Lipid Research, 2007 Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a protease that regulates low density lipoprotein receptor (LDLR) protein levels. The mechanisms of this action, however, remain to be defined.
Yue-Wei Qian +16 more
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