Results 161 to 170 of about 28,830 (248)

Optimization of 4-Amino-2-Pyridone Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9: Integrating Structure-Activity and Structure-Metabolism Relationships. [PDF]

ChemMedChem
Giannessi L, Lupo MG, Ugolotti M, Papotti B, Mattina B, Martina MG, Demurtas A, Padula C, Nicoli S, Crescenzio M, Ferri N, Zimetti F, Radi M.   +12 more
europepmc   +1 more source

Computer-aided design enables repurposing of proprotein convertase subtilisin/kexin type 9 degrader from cholesterol-lowering to colon cancer therapy. [PDF]

Mol Biomed
Fan G, Zha J, Chen S, Cang P, Zhang Q, Yang J, Liu M.   +6 more
europepmc   +1 more source

Prodynorphin Processing by Proprotein Convertase 2 [PDF]

Journal of Biological Chemistry, 1998
Robert Day, Claude Lazure, Ajoy Basak, Alain Boudreault, Paul Limperis, Weijia Dong, Iris Lindberg   +6 more
openaire   +1 more source

Decreasing Proprotein Convertase 5 Causes Hirschsprung's Disease by Disrupting Neural Crest Cell Migration. [PDF]

Cell Mol Gastroenterol Hepatol
Liu Z, Ma Z, Zuo X, Lan C, Chen Y, Liu Z, Zhong W, Chen J, Xie X, Xu X, Wu Q, Huang L, Zeng J, Zhong W, Xia H, Zhang Y.   +15 more
europepmc   +1 more source

The Proprotein Convertase BLI-4 Is Required for Axenic Dietary Restriction Mediated Longevity in Caenorhabditis elegans. [PDF]

Aging Cell
Wu P, Vandemeulebroucke L, Cai H, Braeckman BP.   +3 more
europepmc   +1 more source

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors: A Novel Therapy in the Treatment of Cholesterol Crystal Embolism-Induced Kidney Injury. [PDF]

Kidney Med
Strimaitis BJ, Francis L, O'Sullivan ED.
europepmc   +1 more source

Inhibition of proprotein convertase SKI-1 prevents blood vessel alteration after stroke. [PDF]

Nat Cardiovasc Res
Shabanzadeh AP, Ringuette D, Syonov M, Wu Q, Tassew NG, Mun EK, Meek A, Lively S, Suntharalingham SE, Mojica M, Olijnyk L, Qiang B, Foltz WD, Reed M, Moya I, Brown C, Feng J, Qin X, Akula PS, Wälchli T, Carlen PL, Alcaide-Leon P, Monnier PP.   +22 more
europepmc   +1 more source

Association between proprotein convertase subtilisin/kexin type 9 targeted therapies and the risk of arrhythmias: a meta-analysis of randomized controlled trials. [PDF]

Am J Prev Cardiol
Jaiswal V, Goyal A, Deb N, Shama N, Mittal V, Rajak K, Halder A, Khadka S, Kumar T, Ahmed R, Bytyçi I, Banach M, Lipid and Blood Pressure Meta-Analysis Collaboration (LBPMC) Group.   +12 more
europepmc   +1 more source

LJ-1888, a selective antagonist for the A3 adenosine receptor, ameliorates the development of atherosclerosis and hypercholesterolemia in apolipoprotein E knock-out mice [PDF]

, 2018
Jeong, Lak Shin, Jeong, Se-Jin, Kim, Gyudong, Oh, Goo Taeg, Park, Jong-Gil, Yu, Jinha   +5 more
core   +1 more source

Correction: Reduction of Cardiovascular Risk Using Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors in Patients With Acute Coronary Syndrome: A Systematic Review. [PDF]

Cureus
Rabih AM, Niaj A, Raman A, Uprety M, Calero MJ, Villanueva MRB, Joshaghani N, Villa N, Badla O, Goit R, Saddik SE, Dawood SN, Mohammed L.   +12 more
europepmc   +1 more source