Results 171 to 180 of about 25,303 (250)

Structural insights into proprotein convertase activation facilitate the engineering of highly specific furin inhibitors. [PDF]

Nat Commun
Klaushofer R, Bloch K, Eder LS, Marzaro S, Schubert M, Böttcher-Friebertshäuser E, Brandstetter H, Dahms SO.   +7 more
europepmc   +1 more source

Genetic Pathogenesis of Abdominal Aortic Aneurysm and the Role of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9). [PDF]

Vasc Specialist Int
Choi JY, Gwon JG.
europepmc   +1 more source

Proprotein Convertase Subtilisin/Kexin Type 9 Induces Platelet-Derived Transforming Growth Factor-<i>β</i> to Promote Myocardial Fibrosis After Myocardial Infarction. [PDF]

Hum Mutat
Wang Q, Huang W, Xia D, Wang F, Nair S.
europepmc   +1 more source

Optimization of 4-Amino-2-Pyridone Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9: Integrating Structure-Activity and Structure-Metabolism Relationships. [PDF]

ChemMedChem
Giannessi L, Lupo MG, Ugolotti M, Papotti B, Mattina B, Martina MG, Demurtas A, Padula C, Nicoli S, Crescenzio M, Ferri N, Zimetti F, Radi M.   +12 more
europepmc   +1 more source

Dramatic Coronary Artery Aneurysm Regression After Coronary Artery Bypass Grafting and Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor Therapy. [PDF]

Interdiscip Cardiovasc Thorac Surg
Yokoyama Y, Higashino H, Fujieda H, Abe M.   +3 more
europepmc   +1 more source

Decreasing Proprotein Convertase 5 Causes Hirschsprung's Disease by Disrupting Neural Crest Cell Migration. [PDF]

Cell Mol Gastroenterol Hepatol
Liu Z, Ma Z, Zuo X, Lan C, Chen Y, Liu Z, Zhong W, Chen J, Xie X, Xu X, Wu Q, Huang L, Zeng J, Zhong W, Xia H, Zhang Y.   +15 more
europepmc   +1 more source

The Proprotein Convertase BLI-4 Is Required for Axenic Dietary Restriction Mediated Longevity in Caenorhabditis elegans. [PDF]

Aging Cell
Wu P, Vandemeulebroucke L, Cai H, Braeckman BP.   +3 more
europepmc   +1 more source

Computer-aided design enables repurposing of proprotein convertase subtilisin/kexin type 9 degrader from cholesterol-lowering to colon cancer therapy. [PDF]

Mol Biomed
Fan G, Zha J, Chen S, Cang P, Zhang Q, Yang J, Liu M.   +6 more
europepmc   +1 more source

Comment on: PACE4 (PCSK6): another proprotein convertase linked to iron homeostasis?

Haematologica, 2015
Alessia Pagani, Meriem Ladli, Antonella Nai, Frederique Verdier, Clara Camaschella, Laura Silvestri   +5 more
doaj   +1 more source

Gender differences in the plasma profiles of proprotein convertase subtilisin/kexin-type 9 (PCSK9), soluble low-density lipoprotein receptor (sLDLR), total cholesterol, and triglycerides in patients with colorectal cancer liver metastases: diagnostic and prognostic implications. [PDF]

Lipids Health Dis
Lafortune C, Haddad Y, Marcinkiewicz M, Chrétien M, Turcotte S, Mbikay M.   +5 more
europepmc   +1 more source