Genetic sensitivity to the bitter taste of 6-n-propylthiouracil (PROP) and its association with Physiological mechanisms controlling Body Mass Index (BMI) [PDF]
Nutrients, 2014 Taste sensitivity to the bitter compound 6-n-propylthiouracil (PROP) is considered a marker for individual differences in taste perception that may influence food preferences and eating behavior, and thereby energy metabolism.
Banni S +4 more
core +2 more sources
Acute Liver Failure Associated with Propylthiouracil in a Pregnant 26-Year-Old Woman
Case Reports in Gastroenterology, 2013 It seems appropriate to use propylthiouracil to treat maternal hyperthyroidism during the first trimester of pregnancy. We present the case of a 26-year-old woman with acute liver failure associated with propylthiouracil during the first trimester of ...
Tatsuo Miyamura +9 more
doaj +2 more sources
Propylthiouracil-induced vasculitis with alveolar hemorrhage after 31 years of treatment: a case report [PDF]
Clinical Diabetes and EndocrinologyBackground Propylthiouracil is an antithyroid medication that is associated with ANCA positivity, often in the absence of clinically overt vasculitis. Propylthiouracil-induced ANCA-associated vasculitis (AAV) is characterized by multiple antigenicity and
Ro’a Khalaf +4 more
doaj +2 more sources
Propylthiouracil-induced ANCA-associated vasculitis complicated by granulocytopenia and hemophagocytosis: a case report [PDF]
Frontiers in MedicineObjectiveTo analyze a rare case of ANCA-associated vasculitis (AAV) complicated by hemophagocytosis and granulocytopenia induced by long-term propylthiouracil (PTU) therapy, providing insights for clinical diagnosis and management.MethodsA retrospective ...
Huilin Zhou +5 more
doaj +2 more sources
EFFECT OF PROPYLTHIOURACIL-INDUCED HYPOTHYROIDISM ON REPRODUCTIVE EFFECIENCY OF ADULT MALE RATS [PDF]
Basrah Journal of Veterinary Research, 2013 This study is designed to evaluate the effect of hypothyroidism on reproductive efficiency of adult male rats. Hypothyroid state was induced by administration of anti-thyroid drug propylthiouracil (PTU) (15 mg/kg b.w) orally by gavage for 45 days. Twenty
Jassim.M.A.Alkalby Sarah.J.S.Alzerjawi
doaj +2 more sources
Marked increase in PROP taste responsiveness following oral supplementation with selected salivary proteins or their related free amino acids [PDF]
, 2013 The genetic predisposition to taste 6-n-propylthiouracil (PROP) varies among individuals and is associated with salivary levels of Ps-1 and II-2 peptides, belonging to the basic proline-rich protein family (bPRP).
Aragoni MC +9 more
core +16 more sources
Can propylthiouracil induce autoimmune-related immunotoxicity? [PDF]
Vojnosanitetski Pregled, 2022 Introduction. The use of propylthiouracil can be associated with mild adverse reactions, but severe complications such as agranulocytosis and vasculitis can also be seen.
Bajkin Ivana +4 more
doaj +1 more source
Effect of aqueous rosemary extract on some sexual hormones in male rats with high thyroxine level [PDF]
Iraqi Journal of Veterinary Sciences, 2021 The main purpose of this research is to evaluate the high level of thyroxine affects on each of the luteinizing hormone (LH), testosterone, follicle-stimulating hormone (FSH) of rats and to estimate the potential effect of the administration of aqueous ...
Fouad Z. Hamza +2 more
doaj +1 more source
PLoS ONE, 2022 Background Hyperthyroidism affects about 0.2%-2.7% of all pregnancies, and is generally treated with propylthiouracil (PTU). However, previous studies about the effects of propylthiouracil on maternal or foetal are contentious.
Yiqun Miao +6 more
doaj +2 more sources
Comparison of Propylthiouracil vs Methimazole for Thyroid Storm in Critically Ill Patients.
JAMA Network Open, 2023 Importance Thyroid storm is the most severe form of thyrotoxicosis, with high mortality, and is treated with propylthiouracil and methimazole. Some guidelines recommend propylthiouracil over methimazole, although the difference in outcomes associated ...
S. Y. Lee +5 more
semanticscholar +1 more source