Results 11 to 20 of about 20,653 (230)

Comparison of the safety between propylthiouracil and methimazole with hyperthyroidism in pregnancy: A systematic review and meta-analysis

open access: yesPLoS ONE, 2023
Objective The purpose of this meta-analysis was to assess the safety of the anti-thyroid drugs (ATDs) propylthiouracil (PTU) and methimazole (MMI) in the treatment of hyperthyroidism during pregnancy.
Yue Liu   +4 more
semanticscholar   +1 more source

Propylthiouracil-Induced Antineutrophil Cytoplasmic Antibody-Associated Vasculitis after COVID-19 Vaccination

open access: yesVaccines, 2021
We report the case of a patient who developed antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) after receiving the coronavirus disease 2019 (COVID-19) vaccine BNT162b (Pfizer–BioNTech).
Saki Okuda, Y. Hirooka, M. Sugiyama
semanticscholar   +1 more source

The efficiency and safety of methimazole and propylthiouracil in hyperthyroidism

open access: yesMedicine, 2021
Supplemental Digital Content is available in the text Abstract Purpose: The aim of this study was to evaluate the efficiency and safety of methimazole (MMI) and propylthiouracil (PTU) in the treatment of hyperthyroidism.
Shuang Tan   +3 more
semanticscholar   +1 more source

DRESS/DiHS syndrome induced by Propylthiouracil: a case report

open access: yesBMC Endocrine Disorders, 2023
Background Drug reaction with eosinophilia and systemic symptoms (DRESS), also known as Drug-induced hypersensitivity syndrome (DiHS), is a severe adverse drug reaction. Propylthiouracil, a member of thiouracils group, is widely used in medical treatment
Qiong Shen   +6 more
doaj   +1 more source

Interaction Of Propylthiouracil With Model Systems Generating A Superoxide Radical [PDF]

open access: yesJournal of Biomedical & Clinical Research, 2014
Propylthiouracil is used against Grave's Disease and for developing animal models of hypothyroidism. Apart from depressed metabolism, free radical-induced tissue damage has been registered as an effect from this drug.
Maria Valcheva-Traykova   +2 more
doaj   +3 more sources

Does Withania somnifera mitigate the structural alterations of the rat brain associated with propylthiouracil? [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2022
The repercussion of propylthiouracil (PTU) use postnatally on brain histology have not yet been intensely scrutinized. To examine whether Withania somnifera mitigate the structural effects of propylthiouracil on rat brain, rats were distributed into ...
Luma I. Khalel, Osamah M. Al-Iraqi
doaj   +1 more source

Clinical pharmacology of thyroid and antithyroid drugs [PDF]

open access: yesArhiv za farmaciju, 2022
Autoimmune diseases accompanied by the development of hypothyroidism (Hashimoto's thyroiditis) and hyperthyroidism (Graves' disease) are one of the most common disorders of the thyroid gland.
Stepanović-Petrović Radica   +1 more
doaj   +1 more source

Determining caries risk susceptibility in children of Udaipur city with genetic taste sensitivity and hormonal fingerprint

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2021
Background: Propylthiouracil (PROP) (a medicated tool) and hormonal fingerprint (second to fourth digits [2D:4D]) ratio can be used for detection of caries which is most prevalent oral health disease. Aim: This study aims to determine the role of genetic
Simran Hareshkumar Dusseja   +3 more
doaj   +1 more source

Assessing the Influence of Propylthiouracil and Phenytoin on the Metabolomes of the Thyroid, Liver, and Plasma in Rats

open access: yesMetabolites, 2023
The thyroid hormones (THs) regulate various physiological mechanisms in mammals, such as cellular metabolism, cell structure, and membrane transport.
Zhipeng Wang   +10 more
doaj   +1 more source

Variation in TAS2R receptor genes explains differential bitterness of two common antibiotics

open access: yesFrontiers in Genetics, 2022
For pharmaceuticals to deliver their full benefits with maximum efficacy, patients need to follow recommended dosing schedules, in terms of amount and frequency.
Alissa A. Nolden   +2 more
doaj   +1 more source

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