Results 51 to 60 of about 20,653 (230)
Journal of Biological Chemistry, 2015 Background: Cytochrome b5 reductase 3 (CYB5R3) regulates nitric oxide (NO) diffusion in the artery wall. Results: Novel CYB5R3 small molecule inhibitors were discovered that increase NO bioavailability.
M. Rahaman +12 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li +9 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Objective GLP‐1 receptor agonists (GLP‐1RAs) and SGLT2 inhibitors (SGLT2is) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear. We compared ARD incidence following initiation of GLP‐1RAs, or SGLT2is, vs.
Derin Karacabeyli +4 more
wiley +1 more source
Environmental Toxicology and Chemistry, EarlyView.Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz +9 more
wiley +1 more source
Thyroid Hormone Function in the Rat Testis [PDF]
, 2014 published_or_final_versio
Cheng, CY, GAO, Y, Lee, WWM
core +2 more sources
Genetic variation in the hTAS2R38 taste receptor and food consumption among Finnish adults [PDF]
, 2014 Genetic variation in bitter taste receptors, such as hTAS2R38, may affect food preferences and intake. The aim of the present study was to investigate the association between bitter taste receptor haplotypes and the consumption of vegetables, fruits ...
Hoppu, Ulla +9 more
core +1 more source
Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review
Phytotherapy Research, EarlyView.ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley +1 more source
Fish and amphibians as test organisms for evaluation of effects caused by chemicals [PDF]
, 2007 A large number of chemicals can contaminate aquatic environments and therefore be exposed to fish and amphibians during their sensitive stages of development.
Carlsson, Gunnar
core
Association between TAS2R38 gene polymorphisms and colorectal cancer risk [PDF]
, 2011 Molecular sensing in the lingual mucosa and in the gastro-intestinal tract play a role in the detection of ingested harmful drugs and toxins. Therefore, genetic polymorphisms affecting the capability of initiating these responses may be critical for the ...
Barale, Roberto +23 more
core +1 more source
Propylthiouracil-induced histological changes in the placenta of swiss albino mice
National Journal of Clinical Anatomy, 2020 Introduction: Propylthiouracil, an antithyroid drug, is used to treat hyperthyroidism in early pregnancy as drug of choice. Maternal and fetal morbidities and mortalities occur, if hyperthyroidism is not treated during pregnancy.
Samta Tiwari, S K Pandey
doaj +1 more source