Results 91 to 100 of about 71,694 (241)

Simultaneous monitoring of the two coupled motors of a single FoF1-ATP synthase by three-color FRET using duty cycle-optimized triple-ALEX [PDF]

open access: yes, 2009
FoF1-ATP synthase is the enzyme that provides the 'chemical energy currency' adenosine triphosphate, ATP, for living cells. The formation of ATP is accomplished by a stepwise internal rotation of subunits within the enzyme. Briefly, proton translocation through the membrane-bound Fo part of ATP synthase drives a 10-step rotary motion of the ring of c ...
arxiv   +1 more source

Broccoli and Arthritis: A Review

open access: yesFood Frontiers, EarlyView.
A dietary supplement of broccoli holds potential as a preventive measure against arthritis due to its widespread popularity, safety profile, and affordability. In this systematic review, we have compiled and summarized relevant literature regarding the effects of broccoli and its major bioactive components on arthritis, along with the underlying ...
Mingyuan Song   +5 more
wiley   +1 more source

Monitoring subunit rotation in single FRET-labeled FoF1-ATP synthase in an anti-Brownian electrokinetic trap [PDF]

open access: yes, 2013
FoF1-ATP synthase is the membrane protein catalyzing the synthesis of the 'biological energy currency' adenosine triphosphate (ATP). The enzyme uses internal subunit rotation for the mechanochemical conversion of a proton motive force to the chemical bond.
arxiv   +1 more source

36 degree step size of proton-driven c-ring rotation in FoF1-ATP synthase [PDF]

open access: yesarXiv, 2009
Synthesis of the biological "energy currency molecule" adenosine triphosphate ATP is accomplished by FoF1-ATP synthase. In the plasma membrane of Escherichia coli, proton-driven rotation of a ring of 10 c subunits in the Fo motor powers catalysis in the F1 motor. While F1 uses 120 degree stepping, Fo models predict a step-by-step rotation of c subunits
arxiv  

Optimized green fluorescent protein fused to FoF1-ATP synthase for single-molecule FRET using a fast anti-Brownian electrokinetic trap [PDF]

open access: yes, 2016
Observation times of freely diffusing single molecules in solution are limited by the photophysics of the attached fluorescence markers and by a small observation volume in the femtolitre range that is required for a sufficient signal-to-background ratio. To extend diffusion-limited observation times through a confocal detection volume, A. E. Cohen and
arxiv   +1 more source

Deletion of Microsomal Prostaglandin E Synthase-1 Does Not Alter Ozone-Induced Airway Hyper-Responsiveness

open access: yesJournal of Pharmacology and Experimental Therapeutics, 2010
Nonsteroidal anti-inflammatory drugs ameliorate pain and fever by inhibiting cyclooxygenase (COX) and suppressing prostanoid formation. Microsomal prostaglandin E synthase-1 (mPGES-1) catalyzes formation of PGE2 from the COX product PGH2 and has emerged ...
Miao Wang   +12 more
semanticscholar   +1 more source

Expression and Contribution of Three Different Isoforms of Prostaglandin E Synthase in the Bovine Endometrium1

open access: yesBiology of Reproduction, 2005
Prostaglandins are involved in the regulation of several reproductive processes such as ovulation, luteolysis, and establishment of pregnancy. Prostaglandin E2 (PGE2) appears to favor establishment of pregnancy in most mammals studied so far. The primary
J. Parent, M. Fortier
semanticscholar   +1 more source

Asymmetry of rotational catalysis of single membrane-bound F0F1-ATP synthase [PDF]

open access: yesarXiv, 2007
Erroneous submission in violation of copyright removed by arXiv admin.
arxiv  

Protein glycosylation in lung cancer from a mass spectrometry perspective

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi   +2 more
wiley   +1 more source

Effect of Natural Polyphenols on Breast Cancer Chemoprevention and Treatment

open access: yesMolecular Nutrition &Food Research, EarlyView.
Effect of Natural Polyphenols on Breast Cancer proliferation and progression. ABSTRACT Breast cancer is the most common type of malignancy among women worldwide. Significant achievements have been made in diagnostic tools and cancer treatments in the past decade; however, the complexity and heterogeneity of certain breast cancer subtypes often lead to ...
Marzia Sichetti   +4 more
wiley   +1 more source

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