Results 111 to 120 of about 78,509 (319)

Coordinate up‐ and down‐regulation of glutathione‐dependent prostaglandin E synthase and cyclooxygenase‐2 in A549 cells [PDF]

, 2000
Staffan Thorén, Per‐Johan Jakobsson
openalex   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Overexpression of Functionally Coupled Cyclooxygenase-2 and Prostaglandin E Synthase in Symptomatic Atherosclerotic Plaques as a Basis of Prostaglandin E ₂ -Dependent Plaque Instability [PDF]

, 2001
Francesco Cipollone, Cesaria Prontera, Barbara Pini, Matteo Marini, Maria Fazia, Domenico De Cesare, Annalisa Iezzi, S Ucchino, Gianfranco Boccoli, Vittorio Saba, Francesco Chiarelli, Franco Cuccurullo, Andrea Mezzetti   +12 more
openalex   +1 more source

Immunomodulatory natural polysaccharide‐based nanoparticles for the treatment of neurodegenerative diseases

Ibrain, EarlyView.
Polysaccharide‐based nanoparticles offer versatile platforms for drug delivery and immune modulation in neurodegenerative diseases. This review highlights their potential in treating Alzheimer's, Parkinson's, and multiple sclerosis, focusing on targeted delivery and neuroinflammation.
Leto‐Aikaterini Tziveleka, Mariafrancesca Cascione, Paolo Pellegrino, Annalisa Bianco, Stefano Leporatti, Valeria De Matteis   +5 more
wiley   +1 more source

15-deoxy-Δ12,14-prostaglandin J2 inhibits the expression of microsomal prostaglandin E synthase type 2 in colon cancer cells Published, JLR Papers in Press, March 2, 2006.

Journal of Lipid Research, 2006
Prostaglandin (PG) E2 (PGE2) plays a predominant role in promoting colorectal carcinogenesis. The biosynthesis of PGE2 is accomplished by conversion of the cyclooxygenase (COX) product PGH2 by several terminal prostaglandin E synthases (PGES).
O. Schröder, Y. Yudina, A. Sabirsh, Nadine Zahn, J. Haeggström, J. Stein   +5 more
semanticscholar   +1 more source

Coexpression of Microsomal-Type Prostaglandin E Synthase with Cyclooxygenase-2 in Brain Endothelial Cells of Rats during Endotoxin-Induced Fever [PDF]

, 2001
Kanato Yamagata, Kiyoshi Matsumura, Wataru Inoue, Takuma Shiraki, Kyoko Suzuki, Shin Yasuda, Hiroko Sugiura, Chunyu Cao, Yasuyoshi Watanabe, Shígeo Kobayashi   +9 more
openalex   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

A PUMA-G receptor élettani és kórélettani szerepe az agyi vérkeringésben. = Role of the PUMA-G receptor in the cerebral circulation. [PDF]

, 2010
Eredményeink szerint a PUMA-G receptor nem játszik szignifikáns szerepet az agykérgi véráramlás szabályozásában sem élettani sem pedig kórélettani körülmények között.
Benyó, Zoltán, Hermán, Péter, Horváth, Béla András, Lenzsér, Gábor, Sándor, Péter, Örsy, Petra   +5 more
core  

Microsomal Prostaglandin E Synthase Is Regulated by Proinflammatory Cytokines and Glucocorticoids in Primary Rheumatoid Synovial Cells [PDF]

, 2001
Dirk O. Stichtenoth, Staffan Thorén, Huimin Bian, Marc Peters‐Golden, Per‐Johan Jakobsson, Leslie J. Crofford   +5 more
openalex   +1 more source

Recent Advances in Injectable Hydrogel Biotherapeutics for Regenerative Dental Medicine

Macromolecular Bioscience, EarlyView.
This review analyses multifunctional injectable hydrogels, natural or synthetic, physically or chemically crosslinked, that deliver exosomes, stem cells, and other bioactive cues to inflamed or damaged oral tissues. We discuss their immunomodulatory, antimicrobial, angiogenic, and osteogenic capacities, highlighting advances that enable regenerative ...
Renan Dal‐Fabbro, Arwa Daghrery, Caroline Anselmi, Igor Paulino M. Soares, Alexandre Henrique dos Reis‐Prado, Pedro Henrique Chaves de Oliveira, Marco C. Bottino   +6 more
wiley   +1 more source