Results 291 to 300 of about 236,875 (335)

Calcium transients trigger switch-like discharge of prostaglandin E₂ in an extracellular signal-regulated kinase-dependent manner. [PDF]

Elife
Watabe T, Yamahira S, Takakura K, Thumkeo D, Narumiya S, Matsuda M, Terai K.   +6 more
europepmc   +1 more source

Mitochondrial transfer as a novel therapeutic approach in ischemic stroke treatment: Current challenges and future perspectives

Neuroprotection, EarlyView.
Cerebral ischemia is a serious neurological disease that mainly leads to pathological changes such as mitochondrial dysfunction, oxidative stress and iron death. Mitochondria play a key role in the regulation of cellular energy metabolism and oxidative stress, and their damage can lead to mitochondrial damage, reduced adenosine triphosphate production,
Shuchen Meng, Min Bai, Changsheng Ma, Bo Han, Mengyuan Duan, Liying Zhang, Jinfen Guo, Changku Shi, Ke Li, Maotao He   +9 more
wiley   +1 more source

Role of astrocyte in neuroinflammation‐induced loss in neuroplasticity and subsequent onset of depression: A systematic review

Neuroprotection, EarlyView.
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal, Saurabh Singhal, Bernhard T. Baune   +2 more
wiley   +1 more source

Steroids for Pediatric Adenotonsillectomy Pain—A Prospective Multicenter Randomized Trial

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To compare postoperative caregiver‐reported pain control of two steroid regimens following pediatric adenotonsillectomy. Secondary objectives assessed differences in analgesic use, return to normal diet, caregiver calls, adverse effects, and emergency room (ER) visits. Study Design Prospective randomized pragmatic trial.
Kevin D. Pereira, Wiktoria A. Gocal, Anna V. Borodianski, Mary E. Williamson, Hengameh K. Behzadpour, Sonal Saraiya, Diego A. Preciado, Amal Isaiah   +7 more
wiley   +1 more source

Ibuprofen‐Functionalized Alkyl α‐hydroxy Methacrylate‐Based Polymers

ChemistryOpen, EarlyView.
This work describes the synthesis and evaluation of novel alkyl α‐hydroxymethacrylate‐based ibuprofen‐functionalized prodrugs to improve the bioavailability, decrease toxicity, and control drug release. Novel alkyl α‐hydroxymethacrylate‐based prodrugs are prepared to improve bioavailability, decrease toxicity, and control drug release.
Burcu Balaban, Seckin Altuncu, Aleyna Esenturk, Simay Denizkusu, Ece Sabuncu, Hande Sipahi, Duygu Avci   +6 more
wiley   +1 more source

Correlation between whole salivary prostaglandin E₂ and hemoglobin A1c levels among type-2 diabetic and non-diabetic patients with periodontal inflammation. [PDF]

BMC Oral Health
Shaheen MY, Basudan AM, Alzawawi AS, Al-Ahmari F, Aldulaijan HA, Alshibani N, Shaheen RS, Al-Kattan R.   +7 more
europepmc   +1 more source

19-HydroxyIated E prostaglandins as the major prostaglandins of human semen [PDF]

Nature, 1974
ALMOST 30 years after the initial discovery of the prostaglandins, Bergstrom et al., succeeded in isolating and identifying prostaglandins (PGs) E1, E2, F1α and F2α from sources including human semen1. It was subsequently claimed2 that the 19-hydroxy derivatives of prostaglandins A and B were also present. These compounds were later found at an average
P. L. Taylor, R. W. Kelly
openaire   +2 more sources

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Specific reduction of E prostaglandins to F.alpha. prostaglandins and prostaglandin E2 to prostaglandin E1

Journal of the American Chemical Society, 1971
This is an explanation of 2 highly specific reductive processes for the interconversion of primary PGs (prostaglandins). The laboratory procedures are described in detail and the chemical structures of substances involved in the process are diagrammed. A stereospecific reduction of PGE to PGFalpha is described.
E. J. Corey, Ravi K. Varma
openaire   +3 more sources

Stability of prostaglandin E compounds in solution [PDF]

Lipids, 1973
AbstractIn the present paper the stability of prostaglandins E1, E2, and E3has been studied in two types of solvents: (a) solvents in which they can be used in clinical trials and (b) solvents which are commonly used for their isolation from biological systems.
K. C. Srivastava, J. Clausen
openaire   +2 more sources