Results 301 to 310 of about 236,875 (335)
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Prostaglandins & Other Lipid Mediators, 2002
Prostaglandin E synthase (PGES), which converts cyclooxygenase (COX)-derived prostaglandin (PG)H2 to PGE2, occurs in multiple forms with distinct enzymatic properties, modes of expression, cellular and subcellular localizations and intracellular functions.
Yoshihito Nakatani +3 more
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Prostaglandin E synthase (PGES), which converts cyclooxygenase (COX)-derived prostaglandin (PG)H2 to PGE2, occurs in multiple forms with distinct enzymatic properties, modes of expression, cellular and subcellular localizations and intracellular functions.
Yoshihito Nakatani +3 more
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Prostaglandin E receptors and the kidney
American Journal of Physiology-Renal Physiology, 2000Prostaglandin E2is a major renal cyclooxygenase metabolite of arachidonate and interacts with four G protein-coupled E-prostanoid receptors designated EP1, EP2, EP3, and EP4. Through these receptors, PGE2modulates renal hemodynamics and salt and water excretion. The intrarenal distribution and function of EP receptors have been partially characterized,
Matthew D. Breyer, Richard M. Breyer
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Antidipsogenic role of the E-prostaglandins.
Journal of Comparative and Physiological Psychology, 1978Prostaglandin E1 (PGE1) is antidipsogenic when administered into the lateral cerebral ventricle of the rat. In these experiments PGE1, at a dose of 1 microgram, suppressed water intake induced by centrally administered angiotensin II (AII) or carbachol, subcutaneously administered polyethylene glycol, and water deprivation. Even at this high dose, PGE1
Alan N. Epstein, Nancy J. Kenney
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Prostaglandin E2-induced inflammation: Relevance of prostaglandin E receptors
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2015Prostaglandin E2 (PGE2) is one of the most typical lipid mediators produced from arachidonic acid (AA) by cyclooxygenase (COX) as the rate-limiting enzyme, and acts on four kinds of receptor subtypes (EP1-EP4) to elicit its diverse actions including pyrexia, pain sensation, and inflammation.
Kohichi Kawahara +4 more
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Journal of Endocrinological Investigation, 1980
Prostaglandin (PG) E and 19-OH PGE, now considered to be the most important of the human seminal prostaglandins, were assayed in infertile and normal men. In the 15 volunteers PGE and 19-OH PGE levels were 23-89 microgram/ml, respectively. In the 4 groups of infertile patients in whom either PGE or 19-OH PGE levels were increased or decreased with ...
A. Isidori +4 more
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Prostaglandin (PG) E and 19-OH PGE, now considered to be the most important of the human seminal prostaglandins, were assayed in infertile and normal men. In the 15 volunteers PGE and 19-OH PGE levels were 23-89 microgram/ml, respectively. In the 4 groups of infertile patients in whom either PGE or 19-OH PGE levels were increased or decreased with ...
A. Isidori +4 more
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Prostaglandin E and cancer Growth
Cancer Immunology, Immunotherapy, 1980This paper reviews the evidence linking prostaglandin E (PGE) with the growth of neoplastic tissue. PGE 2 is present in high concentrations in many natural and experimentally produced cancers. The immunosuppressive effect of some tumors in mice is due at least in part to a prostaglandin mechanism.
Ralph C. Williams +2 more
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Difference in Haemodynamic Response to Prostaglandins A and E
Nature, 1971PROSTAGLANDINS A and E are vasodepressor substances, the effect of which has been attributed to direct vasodilator action on peripheral arteriolar smooth muscle1–7. The mechanism of the hypotensive effect of the two prostaglandins may not, however, be identical.
Hartmut Kannegiesser, James B. Lee
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Prostaglandin E in peptic ulcer disease
Prostaglandins, 1974Abstract Prostaglandin E 1 and E 2 inhibit gastric secretion in vivo and in vitro under a variety of conditions. It is not known whether these compounds may play a role in normal gastric secretory physiology or in the pathophysiology of peptic ulcer disease.
Juan J. Engel +2 more
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ChemInform Abstract: STEREOSELECTIVE REDUCTION OF PROSTAGLANDINS E TO PROSTAGLANDINS F
Chemischer Informationsdienst, 1980AbstractDie Prostaglandine E (I) gehen bei der Reduktion mit Li in Tetrahydrofuran und flüssigem Ammoniak in die Prostaglandine Fß(II) über.
K. K. Pivnitskii, V. I. Mel'nikova
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Stability of E-Type Prostaglandins in Triacetin
Journal of Pharmaceutical Sciences, 1979A drug delivery system for E-type prostaglandins is described. In this system, consisting of drug dissolved in triacetin and filled into soft gelatin capsules, normally unstable prostaglandins show excellent stability at room temperature.
T.J. Roseman, Samuel H. Yalkowsky
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