Background Prostaglandin E2 (PGE2) is involved in several chronic inflammatory diseases including periodontitis, which causes loss of the gingival tissue and alveolar bone supporting the teeth. We have previously shown that tumor necrosis factor α (TNFα)
Modéer Thomas+4 more
doaj +1 more source
Retention of differentiated properties in an established dog kidney epithelial cell line (MDCK). [PDF]
Madin-Darby canine kidney (MDCK) cells grown in tissue culture have the morphological properties of distal tubular epithelial cells, form tight junctions, and lack several proximal tubular enzyme markers.
Chuman, LM+3 more
core
Effects of antenatal betamethasone on preterm human and mouse ductus arteriosus: comparison with baboon data. [PDF]
BackgroundAlthough studies involving preterm infants ≤34 weeks gestation report a decreased incidence of patent ductus arteriosus after antenatal betamethasone, studies involving younger gestation infants report conflicting results.MethodsWe used preterm
A El-Khuffash+50 more
core +2 more sources
Prostaglandins and related factors: XIX. Thin-layer chromatography of prostaglandins
Methods are described for separation of all known prostaglandins and some derivatives as free acids and methyl esters by thin-layer chromatography both on analytical and preparative scales. The use of silica gel containing silver nitrate was required for
Krister Gréen, Bengt Samuelsson
doaj
Mechanisms of Inhibitory Effects of Polysubstituted Pyrimidines on Prostaglandin E2 Production
The pyrimidine heterocycle represents an elemental structural motif of numerous drugs. [...]
Zdeněk Zídek+5 more
doaj +1 more source
Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway [PDF]
We report a multiwavelength (X-ray, ultraviolet/optical/infrared, radio) analysis of the relativistic tidal disruption event candidate Sw J2058+05 from 3 months to 3 yr post-discovery in order to study its properties and compare its behavior with that of
Bower, Geoffrey C.+15 more
core +2 more sources
Background Nicotinic acetylcholine (Ach) receptors are ligand-gated pentameric ion channels whose main function is to transmit signals for the neurotransmitter Ach in peripheral and central nervous system.
Minghetti Luisa+3 more
doaj +1 more source
METHOD FOR MODULATING EICOSANOID MEDIATED IMMUNE RESPONSES IN ARTHROPODS [PDF]
The invention is directed to compositions which alter the health of invertebrate organisms by affecting eicosanoid mediated immune responses, and methods of using the compositions.
Stanley, David W.
core +1 more source
Antinociceptive activity of the S1P-receptor agonist FTY720 [PDF]
FTY720 is a novel immunosuppressive drug that inhibits the egress of lymphocytes from secondary lymphoid tissues and thymus. In its phosphorylated form FTY720 is a potent S1P receptor agonist.
Angioni, Carlo Federico+8 more
core +1 more source
mPGES-1-Derived PGE2 Contributes to Indoxyl Sulfate-Induced Mesangial Cell Proliferation
Background/Aims: We previously reported that indoxyl sulfate (IS) could cause mesangial cell (MC) proliferation via a cyclooxygenase (COX)-2-dependent mechanism.
Shuzhen Li+9 more
doaj +1 more source