The role of cyclooxygenase-1 and cyclooxygenase-2 in lipopolysaccharide and interleukin-1 stimulated enterocyte prostanoid formation [PDF]
Mediators of Inflammation, 1998 Lipopolysaccharide is an inflammatory agent and interleukin-1 is a cytokine. Their pro-inflammatory effects may be mediated by prostanoids produced by inducible cyclooxygenase-2.
W. E. Longo +5 more
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Inhibitory effect of esculentoside A on prostaglandin E2 production from murine peritoneal macrophages and rabbit synovial cells in vitro [PDF]
Mediators of Inflammation, 1997 Esculentoside A (EsA) is a saponin isolated from the roots of Phytolacca esculenta. Previous experiments have shown that it has strong antiinflammatory effects.
H-B. Wang, J. Fang, Q-Y. Zheng
doaj +4 more sources
Imbalance of endogenous prostanoids in moderate-to-severe asthma
Allergology International, 2017 Background: Inhalation studies suggested “protective” roles of exogenous prostaglandin E2, but the clinical relevance of endogenous prostanoids in asthma is poorly known. The objective of this study is to measure sputum levels of prostanoids in asthmatic
Masaya Takemura +8 more
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Prostaglandin E2, an Immunoactivator
Journal of Pharmacological Sciences, 2010 Diseases caused by immune inflammation, such as rheumatoid arthritis, multiple sclerosis, and Crohn’s disease, are intractable diseases to which novel therapeutics are highly demanded.
Daiji Sakata +2 more
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Regulation of Immune Responses by Prostaglandin E2 [PDF]
The Journal of Immunology, 2012 PGE2, an essential homeostatic factor, is also a key mediator of immunopathology in chronic infections and cancer. The impact of PGE2 reflects the balance between its cyclooxygenase 2-regulated synthesis and 15-hydroxyprostaglandin dehydrogenase-driven ...
P. Kalinski
semanticscholar +4 more sources
Use of Prostaglandin E2 for Therapeutic Abortion [PDF]
BMJ, 1970 Termination of pregnancy was attempted with intravenous infusion of prostaglandin E(2) (5 mug./minute) in 52 consecutive cases. Abortion was successful in 50 of these and complete in 43. There were no serious side-effects.
S. M. M. Karim, G. M. Filshie
openaire +4 more sources
Pruritogenic activity of prostaglandin E2
Acta Dermato-Venereologica, 1977 The itch and erythematous responses induced by intradermal injection of histamine and PGE2 were studied in human skin. Both compounds produced a sensation of itch. The histamine-elicited flare reached a maximum in 3 min and had disappeared after 1 hours.
O, Hägermark, K, Strandberg
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Modulation of macrophage activation by prostaglandins [PDF]
Mediators of Inflammation, 1996 The effect of prostaglandtn E2, iloprost and cAMP on both nitric oxide and tumour necrosis factor-α release in J774 macrophages has been studied. Both prostaglandin E2 and iloprost inhibited, in a concentration-dependent fashion, the lipopolysaccharide ...
L. Sautebin +3 more
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Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis. [PDF]
PLoS ONE, 2019 BACKGROUND:Prostanoids are important regulators of platelet aggregation and thrombotic arterial diseases. Their involvement in the development of portal vein thrombosis, frequent in decompensated liver cirrhosis, is still not investigated.
Alexander Queck +15 more
doaj +2 more sources
Intravesical prostaglandin e2 effectiveness in the prevention of urinary retention after transvaginal reconstruction of the pubo-cervical fascia and short arm sling according to Lahodny: a prospective randomized clinical trial [PDF]
Urogynaecologia International Journal, 2010 Intravesical prostaglandin E2 is effective in the recovery of spontaneous voiding after transvaginal reconstruction of the pubocervical fascia and short arm sling according to Lahodny.
G. QUADRI +5 more
doaj +3 more sources