Results 11 to 20 of about 214,655 (309)

Prostaglandin E2, an Immunoactivator

Journal of Pharmacological Sciences, 2010
Diseases caused by immune inflammation, such as rheumatoid arthritis, multiple sclerosis, and Crohn’s disease, are intractable diseases to which novel therapeutics are highly demanded.
Daiji Sakata, Chengcan Yao, Shuh Narumiya   +2 more
doaj   +4 more sources

Rotavirus-Mediated Prostaglandin E2 Production in MA104 Cells Promotes Virus Attachment and Internalisation, Resulting in an Increased Viral Load

Frontiers in Physiology, 2022
Rotaviruses are one of the leading causes of severe dehydrating diarrhoea in infants and children under the age of five. Despite the introduction of vaccines, disease burden remains high in sub-Saharan Africa, with no known anti-viral treatments ...
Willem J. Sander, Gabré Kemp, Arnold Hugo, Carolina H. Pohl, Hester G. O’Neill   +4 more
doaj   +1 more source

Dynamics of prostaglandin E2 in the surgical treatment of gastroesophageal reflux disease

Patologìâ, 2023
Gastroesophageal reflux disease (GERD) is one of the most common gastroenterological diseases. Therefore, the issues of diagnosis and the most effective treatment of GERD are extremely relevant.
Ye. I. Haidarzhi
doaj   +1 more source

Timapiprant, a prostaglandin D2 receptor antagonist, ameliorates pathology in a rat Alzheimer’s model

Life Science Alliance, 2022
PGD2 is a major brain prostaglandin and we report that timapiprant that is an antagonist for the PGD2 receptor DP2 reduces pathology and cognitive deficits in a transgenic rat model of Alzheimer’s.
Charles H Wallace, Giovanni Oliveros, Peter A Serrano, Patricia Rockwell, Lei Xie, Maria Figueiredo-Pereira   +5 more
doaj   +1 more source

Is there a difference in labor patterns after induction with prostaglandins and double-balloon catheters?AJOG Global Reports at a Glance

AJOG Global Reports, 2023
BACKGROUND: Labor progression curves are believed to differ between spontaneous and induced labors. However, data describing labor progression patterns with different modes of induction are insufficient.
Hila Shalev-Ram, MD, Roi Cirkin, MD, Gal Cohen, MD, Shai Ram, MD, Yoram Louzoun, MD, Michal Kovo, MD, Tal Biron-Shental, MD   +6 more
doaj   +1 more source

Relationships between prostaglandin concentrations, a single nucleotide polymorphism in HSD17B12, and reproductive performance in dairy cows

Journal of Dairy Science, 2022
: Prostaglandins are involved in multiple processes important for fertility, with previous work in mice highlighting a potential role for the HSD17B12 gene in prostaglandin biosynthesis.
J.L. Juengel, E.M.O. Mosaad, M.D. Mitchell, C.V.C. Phyn, M.C. French, E.D. Meenken, C.R. Burke, S. Meier   +7 more
doaj   +1 more source

Cyclooxygenases and prostaglandin E2 receptors in growth plate chondrocytes in vitro and in situ : prostaglandin E2 dependent proliferation of growth plate chondrocytes [PDF]

, 2006
Prostaglandin E2 (PGE2) plays an important role in bone development and metabolism. To interfere therapeutically in the PGE2 pathway, however, knowledge about the involved enzymes (cyclooxygenases) and receptors (PGE2 receptors) is essential.
Nüsing, Rolf M., Neuland, Pia, Brochhausen, Christoph, Rolf M Nüsing, Günter Klaus, Kirkpatrick, Charles James, Christoph Brochhausen, Klaus, Günter, Pia Neuland, C James Kirkpatrick   +9 more
core   +1 more source

Prostaglandin E Positively Modulates Endothelial Progenitor Cell Homeostasis: An Advanced Treatment Modality for Autologous Cell Therapy [PDF]

, 2009
Aims: The mobilization of endothelial progenitor cells (EPC) and their functioning in postnatal neovascularization are tightly regulated. To identify new modulators of EPC homeostasis, we screened biologically active prostaglandin E compounds for their ...
Hermann, Patrick C., Schwarz, Theresa M., Kopp, Reinhard, Huber, Stephan, Heeschen, Christopher, Herrler, Tanja, Leicht, Simon F.   +6 more
core   +1 more source

Assessment of salivary interleukin-1β (IL-1β), prostaglandin E2(PGE2) levels and pain intensity in children and adults during initial orthodontic treatment

Journal of Orthodontic Science, 2019
OBJECTIVES: To investigate pain intensity, interleukin-1β and prostaglandin E2 values in saliva during initial orthodontic treatment among varying age groups and their correlation between these mediators.
Amrit S Maan, Anand K Patil
doaj   +1 more source

Prostaglandin E2 synthases.

Folia Pharmacologica Japonica, 2002
Prostaglandin E2 (PGE2) is widely distributed in various tissues, and exhibits various biologically important activities. PGE2 synthase (PGES) catalyzes conversion of COX-derived PGH2 to PGE2. It now appears that there are at least three distinct types of PGES in mammals. We identified two distinct glutathione-dependent PGESs.
NAKATANI, Yoshihito, KUDO, Ichiro
openaire   +3 more sources