Results 11 to 20 of about 77,658 (288)
Animal Research and One Health, EarlyView., 2023 In the present study, we created the weight gain models with Min and Yorkshire pigs and conducted the metagenomics and metabolomics of colon contents and transcriptomics of colon tissue. Further, we revealed the characteristics and functions of the colonic microbiota in Min and Yorkshire pigs and analyzed their interactions with the host. Overall, this
Xiaoyu Huang +6 more
wiley +1 more source
Improved homology modeling of the human & rat EP4 prostanoid receptors
BMC Molecular and Cell Biology, 2019 Background The EP4 prostanoid receptor is one of four GPCRs that mediate the diverse actions of prostaglandin E2 (PGE2). Novel selective EP4 receptor agonists would assist to further elucidate receptor sub-type function and promote development of ...
Melissa C. Holt +4 more
doaj +1 more source
Prostaglandin E2 in apical tissue fluid and postoperative pain in intact and teeth with large restorations in two endodontic treatment visits [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2013 Introduction. Acute periapical inflammation is the most common cause of postoperative pain developing as a result of mechanical, chemical and/or microbial injury of periapical tissue.
Grga Đurica +3 more
doaj +1 more source
Mediators of Inflammation, 1998 Lipopolysaccharide is an inflammatory agent and interleukin-1 is a cytokine. Their pro-inflammatory effects may be mediated by prostanoids produced by inducible cyclooxygenase-2.
W. E. Longo +5 more
doaj +1 more source
Imbalance of endogenous prostanoids in moderate-to-severe asthma
Allergology International, 2017 Background: Inhalation studies suggested “protective” roles of exogenous prostaglandin E2, but the clinical relevance of endogenous prostanoids in asthma is poorly known. The objective of this study is to measure sputum levels of prostanoids in asthmatic
Masaya Takemura +8 more
doaj +1 more source
Termination of Pregnancy: Misoprostol Versus Prostaglandin E2
Pakistan Armed Forces Medical Journal, 2023 Objective: To compare the efficacy of vaginal Misoprostol and vaginal prostaglandin E2 in termination of pregnancy. Study Design: Quasi-experimental study.
Imama Tul Bushra +5 more
doaj +1 more source
Ensho Saisei, 2000 Prostaglandin E synthase (PGES) catalyzes isomerization of PGH2to PGE2which exhibits potent and various biological activities. Here we report the molecular identification of two distinct glutathione-dependent PGESs, the terminal PGE2-biosynthetic enzymes of the cyclooxygenase (COX) pathway.
Yoshihito Nakatani +2 more
openaire +2 more sources
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Frontiers in Pharmacology, 2020 RationaleThe development of inhibitors of microsomal prostaglandin (PG)E2 synthase-1 (mPGES-1) was driven by the promise of attaining antiinflammatory agents with a safe cardiovascular profile because of the possible diversion of the accumulated ...
Luigia Di Francesco +12 more
doaj +1 more source
Urogynaecologia International Journal, 2010 Intravesical prostaglandin E2 is effective in the recovery of spontaneous voiding after transvaginal reconstruction of the pubocervical fascia and short arm sling according to Lahodny.
G. QUADRI +5 more
doaj +1 more source