Results 71 to 80 of about 77,658 (288)

The role of cyclooxygenase-2 (COX-2) and inflammatory markers in the progress of Alport syndrome in Egyptian children

open access: yesBMC Pediatrics
Background Chronic inflammation and its control are crucial to the responses of glomerular and renal tubular cells. This contributes to the pathogenic mechanisms and advancement of the disease in Alport syndrome.
Moushira Zaki   +8 more
doaj   +1 more source

Stress induced experimental colitis

open access: yesMediators of Inflammation, 1993
Stress induces chemical changes in the central nervous system which alters the biochemistry and physiology of the digestive tract. The present study determines arachidonic acid oxidation and damage in the colon following stress. Ten rats were stressed by
T. A. Stein   +4 more
doaj   +1 more source

An observational study comparing two regimens of PGE2 gel for pre-induction cervical ripening at term [PDF]

open access: yesNew Indian Journal of OBGYN
Objectives: The objective of this study was to compare the outcome in between two groups, one group receiving a 6 hourly repeat regimen (maximum 2 such) and another group receiving a 12 hourly repeat regimen of prostaglandin E 2 gel (maximum 2 such ...
Nishat Parveen Begg   +2 more
doaj   +1 more source

Prostaglandin E2: igniting the fire [PDF]

open access: yesImmunology & Cell Biology, 2009
Chizzolini Carlo, Brembilla Nicolò C
openaire   +2 more sources

Induction of Abortion by Prostaglandins E1 and E2 [PDF]

open access: yesBMJ, 1970
Intravenous infusions of prostaglandin E (E(1) or E(2)) were used for termination of pregnancy in 11 patients. Induction of abortion was successful in nine instances and in eight the abortion was complete. No undesirable side-effects were recorded.
openaire   +3 more sources

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

open access: yesIbrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Prostanoid-dependent bladder pain caused by proteinase-activated receptor-2 activation in mice: Involvement of TRPV1 and T-type Ca2+ channels

open access: yesJournal of Pharmacological Sciences, 2018
We studied the pronociceptive role of proteinase-activated receptor-2 (PAR2) in mouse bladder. In female mice, intravesical infusion of the PAR2-activating peptide, SLIGRL-amide (SL), caused delayed mechanical hypersensitivity in the lower abdomen ...
Maho Tsubota   +7 more
doaj   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

open access: yesIbrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Immunomodulatory natural polysaccharide‐based nanoparticles for the treatment of neurodegenerative diseases

open access: yesIbrain, EarlyView.
Polysaccharide‐based nanoparticles offer versatile platforms for drug delivery and immune modulation in neurodegenerative diseases. This review highlights their potential in treating Alzheimer's, Parkinson's, and multiple sclerosis, focusing on targeted delivery and neuroinflammation.
Leto‐Aikaterini Tziveleka   +5 more
wiley   +1 more source

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