Results 1 to 10 of about 277,845 (352)

Cytoprotection by prostaglandins

open access: yesGastroenterology, 1979
Prostaglandins (PG) are a group of ZO-carbon oxy- genated fatty acids that are present in most mamma- lian cells and tissues. Approximately 20 of these chemicals have been identified in tissues and body fluids, whereas hundreds have been synthesized as analogs or derivatives of the natural PG.
A. Robert
openaire   +5 more sources

Lactones in the Synthesis of Prostaglandins and Prostaglandin Analogs [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
In the total stereo-controlled synthesis of natural prostaglandins (PGs) and their structural analogs, a vast class of compounds and drugs, known as the lactones, are encountered in a few key steps to build the final molecule, as: δ-lactones, γ-lactones, and 1,9-, 1,11-, and 1,15-macrolactones.
Constantin Tănase   +2 more
openaire   +2 more sources

PROSTAGLANDINS

open access: yesThe Lancet, 1968
Observations from 1930 to 1934 have indicated autopharmacological effects of human seminal fluid. The active principle was shown to be an unsaturated lipid‐soluble acid. After isolation in 1960 of two closely related compounds, the chemical constitution was established.
openaire   +7 more sources

Prostaglandins and prostaglandin receptor antagonism in migraine [PDF]

open access: yesThe Journal of Headache and Pain, 2013
Human models of headache may contribute to understanding of prostaglandins' role in migraine pathogenesis. The current thesis investigated the migraine triggering effect of prostaglandin E2 (PGE2) in migraine patients without aura, the efficacy of a novel EP4 receptor antagonist, BGC20-1531, in prevention of PGE2-induced headache and the ability of ...
openaire   +3 more sources

Biosynthesis of Prostaglandins [PDF]

open access: yesAnnual Review of Nutrition, 1991
Highly purified cyclooxygenase from sheep vesicular glands is stimulated by the presence of protoporphyrin IX compounds. This stimulation may be due to the conversion of an apoenzyme to the holoenzyme, and full activity is achieved when half of the enzyme subunits (70,000 daltons) bind heme.
openaire   +3 more sources

Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis. [PDF]

open access: yesCochrane Database Syst Rev
Gallos ID   +7 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy