Results 81 to 90 of about 64,031 (206)

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

open access: yesHepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog   +12 more
wiley   +1 more source

The Consequences of Preterm Birth and Chorioamnionitis on Brainstem Respiratory Centers: Implications for Neurochemical Development and Altered Functions by Inflammation and Prostaglandins

open access: yesFrontiers in Cellular Neuroscience, 2018
Preterm birth is a major cause for neonatal morbidity and mortality, and is frequently associated with adverse neurological outcomes. The transition from intrauterine to extrauterine life at birth is particularly challenging for preterm infants. The main
Vanesa Stojanovska   +6 more
doaj   +1 more source

Metabolomic analysis reveals the molecular mechanism related to leg abnormality in broilers

open access: yesAnimal Research and One Health, EarlyView.
The graphical abstract shows the principal results of this study. Compared to the leg normal broilers, the serum calcium to phosphorus ratio was extremely decreased in the group with deformed leg bones. Additionally, a total of nine differential metabolites significantly associated with leg abnormalities and serum calcium and phosphorus levels were ...
Jumei Zheng   +9 more
wiley   +1 more source

Khronicheskoe legochnoe serdtse:klassifikatsiya, klinika, diagnostika,lechenie. Chast' I

open access: yesКардиоСоматика, 2011
Summary. In the first part of this review both domestic and foreign data from clinical and experimental researches relating to modern views on the definition, classification, clinical and morphological picture, as well as approaches to the treatment of ...
Ol'ga Vladimirovna Polyakova   +1 more
doaj  

NSAIDs in orthodontic tooth movement

open access: yesJournal of Pharmacy and Bioallied Sciences, 2012
Orthodontic tooth movement is basically a biological response toward a mechanical force. The movement is induced by prolonged application of controlled mechanical forces, which create pressure and tension zones in the periodontal ligament and alveolar ...
Muthukumar Karthi   +5 more
doaj   +1 more source

Sirt5 regulates chondrocyte metabolism and osteoarthritis development through protein lysine malonylation

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives Chondrocyte metabolic dysfunction plays an important role in osteoarthritis (OA) development during aging and obesity. Protein post‐translational modifications (PTMs) have recently emerged as an important regulator of cellular metabolism. We aim to study one type of PTM, lysine malonylation (MaK) and its regulator Sirt5 in OA development ...
Huanhuan Liu   +11 more
wiley   +1 more source

Arachidonic acid-dependent gene regulation during preadipocyte differentiation controls adipocyte potential[S]

open access: yesJournal of Lipid Research, 2014
Arachidonic acid (AA) is a major PUFA that has been implicated in the regulation of adipogenesis. We examined the effect of a short exposure to AA at different stages of 3T3-L1 adipocyte differentiation.
Evanthia Nikolopoulou   +6 more
doaj  

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