Results 201 to 210 of about 74,984 (316)

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa, Birhanetensay Masresha Altaye, Yuh‐Pyng Sher   +2 more
wiley   +1 more source

Using combined ROC curves to improve the diagnostic usefulness of glutaminase, prostaglandins, and 8-isoprostane as biomarkers of autism spectrum disorders;Role in the Glu-GABA-Gln cycle. [PDF]

BMC Neurosci
El-Ansary A, Alfawaz HA, Alhakbany M, Bhat RS, Bjørklund G, Al-Ayadhi LY.   +5 more
europepmc   +1 more source

Melatonin Promotes Improvement in Serum Lipid Levels and Liver Histopathology in Hyperlipidemic Rats

Lipids, EarlyView.
ABSTRACT Hyperlipidemia or dyslipidemia is the term used for the increase in lipid levels in blood plasma, usually occurring due to a high‐fat diet associated with a sedentary lifestyle. The increase in lipid levels can cause fatty infiltration in the liver known as hepatic steatosis, which can lead to inflammation, fibrosis, and necrosis consecutively.
Ana Cláudia Carvalho de Sousa, Jaiurte Gomes Martins da Silva, Érique Ricardo Alves, Laís Caroline da Silva Santos, Bruno José do Nascimento, Marcelle Mariana Sales de França, Vanessa Bischoff Medina, Ismaela Maria Ferreira de Melo, Álvaro Aguiar Coelho Teixeira, Valéria Wanderley Teixeira   +9 more
wiley   +1 more source

Comparison of Different Methods of Labor Induction and Their Maternal and Neonatal Outcomes: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Okobi OE, Oladimeji A, Durojaiye IA, Adewara O, Mochu AW, Shofu O, Adedoyin AM, Arifayan SO.   +7 more
europepmc   +1 more source

β‐Aminoisobutyric Acid Alleviates Cisplatin‐Induced Muscle Atrophy by Regulating E3 Ubiquitin Ligases, Apoptosis, Amino Acid Metabolism, Autophagy, and Ferroptosis

Medicine Bulletin, EarlyView.
ABSTRACT Background Cisplatin (CIS) is a widely used broad‐spectrum anticancer agent, but its clinical application is often limited by severe adverse effects, including skeletal muscle atrophy, which compromises patients' quality of life and treatment efficacy.
Hao‐Zhe Wang, Wen‐Bi He, Huan Wang, Hao Wang, Wen‐Jun Fang, Meng‐Qian Li, Jiong‐Xing Huang, Fei‐Peng Chen, Hui‐Guo Wang, Lin Zhu, Xiao‐Guang Liu   +10 more
wiley   +1 more source

Mechanistic Insights Into Photobiomodulation for Primary Dysmenorrhea: A Narrative Review. [PDF]

Cureus
Pelevin E, Pabian L, Auerbach S, Ballard A, Goempel J, Jiang L, Oro J, Searles J, Sloan K, Walter E, Bouras A, Jacobs RJ.   +11 more
europepmc   +1 more source

Intraoperative Cardiac Events During Pediatric Cardiac Magnetic Resonance Imaging Under Anesthesia: A Retrospective Cohort Study

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Children with congenital heart disease (CHD) frequently undergo cardiac magnetic resonance imaging (MRI) under anesthesia. Although these procedures lack surgical stimulus, patients remain physiologically vulnerable, and the incidence of perioperative cardiovascular instability in this setting is poorly defined.
Theodora Wingert, Justine Liang, Kelly Feldman, Amelie Delaporte, Christine Nguyen‐Buckley, Tristan Grogan, Alexandre Joosten, John Paul Finn, Ihab Ayad   +8 more
wiley   +1 more source

The Role of Prostaglandins as Major Inflammatory Mediators in Colorectal Cancer. [PDF]

Int J Mol Sci
Macia Guardado M, Lutz V, Hengstschläger M, Dolznig H.   +3 more
europepmc   +1 more source

Rehabilitation and return to activity after platelet‐rich plasma injections in chronic tendinopathies: Consensus from international experts

PM&R, EarlyView.
Abstract Background The effectiveness of platelet‐rich plasma (PRP) injections in chronic tendinopathies remains debated. Although the product's characteristics play a role, the impact of postinjection recommendations remains poorly investigated. Objective To establish principles and guidelines for post‐PRP injection rehabilitation and return to ...
Vincent Gremeaux, Martin Lamontagne, Valérie Bélanger, Etienne Dalmais, Eric Noël, Alain Frey, Paul Ornetti, Fadoua Allali, Jimmy Gross, F. Michel, Hervé Bard, Jean‐François Kaux, the GRIIP (Groupe de Recherche International sur les Injections de Plaquettes; International Research Group on Platelet Injections)   +12 more
wiley   +1 more source

Identification and characterization of prostaglandin F_2α 9-dehydrogenase from Rhodotorula kratochvilovae. [PDF]

Appl Microbiol Biotechnol
Shino U, Yagi K, Munesato K, Takeuchi M, Yamamura ET, Nagano H, Park SB, Watanabe H, Ando A, Ueda M, Ogawa J.   +10 more
europepmc   +1 more source