ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei +6 more
wiley +1 more source
Lipidomic analysis reveals drug-induced lipoxin synthesis in glaucoma treatment. [PDF]
Mathew DJ +12 more
europepmc +1 more source
Abstract Background Data evaluating paracetamol combined with NSAIDs in dogs are scarce. Results of clinical studies in dogs investigating intravenous paracetamol vary. Methods Dogs were randomised to either receive 10 mg/kg paracetamol intravenously after induction of anaesthesia and every 8 hours during hospitalisation (test) or not (control).
Robin Stallard +2 more
wiley +1 more source
Prostaglandin E2-induced inflammation: Relevance of prostaglandin E receptors
Prostaglandin E2 (PGE2) is one of the most typical lipid mediators produced from arachidonic acid (AA) by cyclooxygenase (COX) as the rate-limiting enzyme, and acts on four kinds of receptor subtypes (EP1–EP4) to elicit its diverse actions including pyrexia, pain sensation, and inflammation.
openaire
Modulation of mouse NK activity by Prostaglandins, Thymosin alfa1 and Interferon.
JEZZI T. +5 more
core
The IRE1 α -XBP1s-NF κ B axis controls cell survival and epithelial differentiation under osmotic stress through arachidonic acid metabolism activation. [PDF]
Parra LG +6 more
europepmc +1 more source
Staging concept for aging management: Definition, mechanism, and coping strategies
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang +6 more
wiley +1 more source
Tolerability of 0.5% Liposomal Ozonated Oil Versus 0.6% Povidone-Iodine in Antiseptic Prophylaxis for Intravitreal Injections. [PDF]
Pastore MR +7 more
europepmc +1 more source
Gut microbiota dysbiosis and Long COVID susceptibility in chronic kidney disease
This study investigated gut microbiota dysbiosis and its association with Long COVID susceptibility in 224 hemodialysis patients. We found that 35.3% of patients developed Long COVID, characterized by neurological symptoms and elevated inflammatory markers, accompanied by significant gut microbiota alterations including enriched proinflammatory taxa ...
Meiling Jin +5 more
wiley +1 more source
Lactate values during labour and their correlation with maternal and fetal outcome. [PDF]
Milan B +8 more
europepmc +1 more source

