Results 231 to 240 of about 141,844 (309)

Hypothalamic Prostaglandins Facilitate Recovery From Severe Hypoglycemia but Exacerbate Recurrent Hypoglycemia in Mice. [PDF]

Diabetes
Abe T, Xu S, Sugiura Y, Arima Y, Hayasaka T, Lee ML, Ishimoto T, Araki Y, Ngurari S, Niu Z, Iijima N, Diano S, Toda C.   +12 more
europepmc   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Structure and transport mechanism of the human prostaglandin transporter SLCO2A1. [PDF]

Nat Commun
Xia Z, Lu G, Wu D, Zhao J, Zhang B, Xu H, Du Y, Jiang D.   +7 more
europepmc   +1 more source

Metabolic engineering of adipose‐derived stem cell exosomes via arachidonic acid potentiates diabetic wound repair by orchestrating angiogenesis: A multi‐omics guided strategy

VIEW, EarlyView.
AA‐Exos promotes angiogenesis and accelerates diabetic wound healing by activating the PI3K/AKT/mTOR pathway. Abstract Diabetic wounds are common and challenging complications of diabetes, characterized by delayed healing and an increased risk of infection.
Yujiao Cai, Jinnan Wang, Yan Liu, Xiaoke Zhu, Zhanyuan Yuan, Weiling Li, Dehui Che, Dongsheng Cao   +7 more
wiley   +1 more source

Improved de novo production of prostaglandin F_2α from glucose with engineered Yarrowia lipolytica strains. [PDF]

Commun Biol
He GW, Ding LM, Fan X, Wang C, Lu XY, Tian Y, Ji XJ, Huang H, Liu HH.   +8 more
europepmc   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

Essential oil from Eugenia stipitata McVaugh leaves exhibits antinociceptive effect via opioid receptor activation. [PDF]

Inflammopharmacology
Costa WK, Dos Santos de Moraes PG, Souza JGE, do Nascimento Silva PHA, Dantas HA, da Silva EK, Galvão LRL, da Silva Freitas TS, de Souza TVF, de Oliveira AM, da Silva MV, Dos Santos Correia MT.   +11 more
europepmc   +1 more source

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Association of muscle instability and long-term prophylaxis in hereditary angioedema. [PDF]

World Allergy Organ J
Hollers E, Yu Y, Sheetz J, Richwine K, Grim K, Germak-Sovereign R, Luong L, Hitomi H, Al-Shaikhly T, Craig T.   +9 more
europepmc   +1 more source

Mechanical signalling in osteoarticular tissues [PDF]

, 2010
Lee, Herng-Sheng, Salter, Donald
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